Institute Physics & Chemical Research, Kanagawa
PKC epsilon is linked to insulin resistance via plasma IL-6 regulation
Published in Healthcare Mergers, Acquisitions and Ventures Week, April 16th, 2005
"Recent reports have suggested that PKC epsilon contributes to systemic insulin resistance, and is involved in the pathogenesis of type 2 diabetes, however, the exact mechanism is still unknown," researchers in Japan reported in a recent issue of the journal Biochemical and Biophysical Research Communications.
"To elucidate the possible involvement of PKC epsilon in the pathogenesis of type 2 diabetes, we examined the role of PKC epsilon in differentiated adipocytes using mouse 3T3-LI adipocytes," explained K. Ohashi and colleagues.
The researchers...
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