University of Amsterdam
Researchers publish new studies and findings in the area of oncology
Published in Healthcare Mergers, Acquisitions and Ventures Week, April 16th, 2005
Study 1: Gelatinase inhibitors warrant scrutiny when used as cancer therapy.
According to a review from the Netherlands, "various proteases are involved in cancer progression and metastasis. In particular, gelatinases, matrix metalloproteinase-2 (MMP-2) and MMP-9, have been implicated to play a role in colon cancer progression and metastasis in animal models and patients. In the present review, the clinical relevance and the prognostic value of messenger ribonucleic acid (mRNA) and protein expression and proenzyme activation of MMP-2 and MMP-9 are evaluated in relation to...
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