Novo Nordisk
Increase in hypothalamic levels of histamine reduces food intake and body weight
Published in Healthcare Mergers, Acquisitions and Ventures Week, January 14th, 2006
According to a study from Denmark, "This study was conducted to elucidate whether antagonistic targeting of the histamine H3 receptor increases hypothalamic histamine levels, in parallel with decreases in food intake and body weight."
K. Malmlof and colleagues at Novo Nordisk explained, "The competitive antagonist potency of a recently synthesized histamine H3 receptor antagonist, NNC 38-1049, was studied in intact HEK293 cells expressing human or rat histamine H3 receptor, in which NNC 38-1049...
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