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Healthcare Mergers, Acquisitions and Ventures Week

Susan Hasty, Publisher

Table of Contents . . . February 11th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Healthcare Mergers, Acquisitions and Ventures Week | Other Publications

Acacia Research Corporation - CombiMatrix to become independent public company

Acadia Pharmaceuticals, Inc. - Pharmaceutical company reports additional $10M equity investment by Sepracor

Advance Nanotech, Inc. - Nanotech firm appoints Claudio Marinelli as entrepreneur-in-residence

Advanced BioPhotonics Inc. - Medical imaging company restructures and reduces board of directors

Advanced BioPhotonics, Inc. - Imaging company closes on second financing milestone

Advanced Magnetics, Inc. - Imaging agent developer reports loss of $0.43 per share

Akorn, Inc. - Ophthalmic drug developer retires series A preferred stock

Aksys, Ltd. - Dialysis systems developer reports $20M stock purchase agreement

Allergan, Inc. - Regulatory approvals granted by Germany, Spain for exchange offer with Inamed Corp.

Alltracel Pharmaceuticals Plc. - Wound care developer reports revenues of EUR 5.7M

Alnylam Pharmaceuticals, Inc. - RNAi therapeutics company aims to finish 2006 with greater than $50 million in cash

Alnylam Pharmaceuticals, Inc. - U.S. patent allowed which broadly covers RNAi therapeutics

American Medical Systems Holdings, Inc. - Erectile dysfunction device maker posts 22% growth in fourth quarter

American Oriental Bioengineering, Inc. - Institutional coverage for nutritional supplements maker initiated by Investrend Research

AmerisourceBergen Corp. - Pharmaceutical services company raises operating revenue growth expectations

AMDL, Inc. - Cancer diagnostics company may purchase two Chinese pharmaceutical firms

Academic Medical Center, Amsterdam - Heart rate response to exercise doesn't affect cardiac output or cerebral perfusion

Accreditation - URAC says enhanced patient safety, quality improvement central to its revised standards

Adlyfe, Inc. - Protein detection technology developer secures $3.3M in series A round

Agilent Technologies, Inc. - Dual-mode gene expression microarray platform launched

Amarin Corp. plc - Promising preclinical data reported from Parkinson disease program investigating Miraxion

American Chiropractic Association - Chiropractic group endorses footwear

American Hospital, Reims - Efficacy of chemotherapy compared to bone marrow transplantation in leukemia

Amgen - Human Genome Sciences signs agreement for autoimmune disease therapy

ApoPharma - Ferriprox prevents iron-induced heart disease and reduces cardiac death risk in thalassemia

Arena Pharmaceuticals, Inc. - Obesity drug maker announces public offering of common stock

Array BioPharma, Inc. - Phase I trial initiated for targeted anticancer drug ARRY-334543

Arrowhead Research Corp. - Nanotechnology firm announces sale of more than 5M shares

Berlex Biosciences - Adenovirus genome insertion sites utilize splicing machinery for therapeutic gene expression

Biopure Corp. - Oxygen therapeutics maker closes $3M financing

Biovail Corp. - Approval granted for Wellbutrin XL to treat depression in Canada

Business Update - APS Healthcare grows health management business

CNRS, Meylan - Piperazinobenzopyranones and phenalkylaminobenzopyranones inhibited ABCG2

CRP Sante, Luxembourg - HAART interruption and resistance mutation emergence causes virological failure

Cardiff University - Discriminant analysis can identify potential transdermal enhancers

Celje General Hospital - Etidronate fails to prevent periprosthetic bone loss after cemented hip arthroplasty

Cell Signaling Technology, Inc. - Agreement inked with AstraZeneca to evaluate PhosphoScan platform

Children's Hospital of Philadelphia - Review focuses on out-of-hospital pediatric cardiac arrest epidemiology

China Medical University Hospital - Elevated triglycerides and body weight could be linked to olanzapine use

Ciudad Universitaria Cantoblanco - Studies advance knowledge in vaccines vector research

Claude Bernard University, Lyon - Novel porous titanium surface has high biocompatibility and electrochemical performance

Clemson University - Pure arterial elastin and collagen scaffolds rally support for tissue growth

Cleveland Clinic - Bcl-X L gene transfer is neuroprotective in models of motor neuron disease

Cleveland Clinic Foundation - DexAide right ventricular assist device performs well in early animal tests

Connetics Corp. - Specialty-pharmacy company acquires PediaMed sales organization

Cutting Edge Information - Blockbuster drugs are backed with big budgets

Dana-Farber Cancer Institute - Variation in IGF-1 gene associated with increased cancer risk

Democritus University of Thrace, Alexandroupolis - Strategies provided for preventing radiation induced xerostomia

Deutsches Kinderherzzentrum Sankt Augustin - Successful biodegradable metal stent implantation in preterm baby is reported

Diet & Nutrition - Whole grain foods are better at all ages

Encysive Pharmaceuticals - Dose-ranging study of TBC3711 begins

EntreMed, Inc. - Acquisition of Miikana Therapeutics complete

Ewha Womans University, Seoul - A ginseng saponin metabolite may fight cancer by blocking matrix metalloproteinase

Federal University of Juiz de Fora - Autogenous tissue implanted in abdomen cavity acts similar to intact spleen

Florida A & M University, Tallahassee - COX-2 inhibitor augments the anticancer properties of docetaxel in lung tumors

Forbes Medi-Tech, Inc. - Reducol-based products available at Tesco Stores

Fox Chase Cancer Center, Philadelphia - Antisense Bcl-2 sensitizes prostate cancer cells to radiation

Frost & Sullivan - Study shows computational biology tools are key to improving drug discovery process

Genzyme Corp. - Researchers report details of new studies and findings in the area of oncology

Genzyme Corporation - Biotech company reports 22% increase in fourth-quarter revenue

Georgetown University, Washington, DC - The shared-decision model benefits pediatric medicine by increasing parental satisfaction

Gersthof Orthopedic Clinic, Vienna - Anterior windowing of femur diaphysis effective for cement removal

Hadassah University Hospital, Jerusalem - Herpetic eye disease is more common among diabetics and diabetics with poor glycemic control

Harris Interactive - Poll finds majorities of U.S. adults do not believe abstinence programs are effective

Hokkaido University School of Medicine - Hypertension risk factors during pregnancy may provide insight into pathophysiology

Hvidovre University Hospital - Insulin resistance mechanisms enhance type 2 diabetes risk in HIV lipodystrophy

Hyland's, Inc. - Homeopathic drugs regulated more like conventional drugs than dietary supplements

INSERM U593, Bordeaux - Report describes infant feeding practices in Abidjan, Cote d'Ivoire

Inflazyme Pharmaceuticals Ltd. - New director Louis Drapeau named chairman of pharmaceutical company's audit committee

Information Technology - Forte releases latest 8000 series Practice Management software

Information Technology - Oldest Tennessee hospital installs software to record and access patient information

Inovio Biomedical Corp. - Partnership signed to develop vaccine for hepatitis C

Institut de Recerca Oncologica, Barcelona - Findings in cancer vaccines provide new insights

Intercell AG - Sanofi pasteur makes milestone payment for bacterial vaccine development

Jichi Medical School, Tochigi - Genomic fragments methylated specifically in colorectal carcinoma screened

Juvaris BioTherapeutics, Inc. - U.S. NIH NIAID awards 2-year grant for development of influenza A virus vaccine

Kyphon Inc. - Two-year balloon kyphoplasty data show improvement of pain and function

LEO Pharma - U.S. FDA approves a once-daily therapy for treatment of psoriasis

Lantibio, Inc. - Pharma companies announce agreement for U.S. development and marketing of Vismed

MRC, London - Recent HIV-1 seroconverters more likely to have transmitted drug resistance

Massachusetts General Hospital - Study identifies molecule essential for proper localization of blood stem cells

Mayo Clinic - Novel cryothermal balloon ablation system shows promise for pulmonary vein isolation

MedPanel - Medical market intelligence company launches information service for non-Hodgkin lymphoma

Medical Devices - VCU Medical Center combines technologies to enable image-guided radiosurgery

Medical University of Silesia - Contemporaneous carrier-state of 2 or 3 gene variants differentiates CAD

Medical University of Vienna - Model-based analysis of ECG-gated 13N-NH3 PET images determines LV data accurately

Mera Pharmaceuticals - Hawaii-based biotech firm forms new divisions

Monash University, Clayton - Oral contraceptive pretreatment assists in vitro fertilization

NanoViricides, Inc. - Vietnam government enters collaboration to develop drug to treat bird flu

National Taiwan University, Taipei - Cytokine and DNA repair gene variations contribute to to hepatitis B virus-related HCC

Northwestern University, Chicago - T-bet controls selectin ligand expression in Th1 cells

Novartis Consumer Health - Diclofenac gel reported effective and safe for relief of symptoms of knee osteoarthritis

Novo Nordisk - NordiFlex multidose growth hormone pen can now be kept unrefrigerated after initial use

Oita University - Research add new data to diabetes therapy body of knowledge

Oklahoma State University - Tick antigen vaccine controls Ixodes scapularis adult infestations

Oregon Health Science University - Commentary addresses the involvement of ghrelin in metabolic signaling

Organization for Hospital Excellence, Inc. - Online resource launches to assist with change in healthcare organizations

Orthopedic Healthcare Northwest, Eugene - Sequential bilateral total hip arthroplasty safely performed in single hospitalization

Personnel - Crdentia announces promotions of Cahillane, Emery, Ross, and Turnbull

Personnel - Kathy Zorica named head of Wellpoint's under 65 individual market for central region

Personnel - TeamHealth announces resignation of executive VP of finance Robert Abramowski

Phytopharm plc - Pharma company enters marketing and distribution agreement for Phytopica

Piribo Ltd - Survey finds generics top-of-mind for pharmaceutical executives in 2005

Possis Medical, Inc. - Italy clinical trial site enrolls and treats first patients in Angiojet thrombectomy trial

Prince Charles Hospital, Chermside - Routine drain tip culture not recommended for diagnosis of postarthroplasty infection

Quality Assurance - Report: Monitoring system needed to prevent safety hazard of problem physicians

Radiotherapy - Radiotherapy staff shortage in U.K. may be putting cancer patients at risk

Randers Central Hospital - Graft fixation type is key factor in tunnel widening after hamstring ACL reconstruction

Replidyne, Inc. - Biopharma company submits NDA for Orapem to treat respiratory tract and skin infections

Research Center Borstel - Lipopeptide structure determines TLR2 dependent cell activation level

Rite Aid Corporation - Retail drug store chain reports 3.8% same-store sales increase for December 2005

Royal Free & University College Medical School, London - Presence of metabolic syndrome is predictor of coronary heart disease and type 2 diabetes

Sanochemia Pharmazeutika AG - Neuroactive compound licensed by Avigen for disabling neuromuscular conditions

Schering, AG - Climara Pro receives U.S. approval for osteoporosis prevention

Singapore Sports Council - Maximal oxygen uptake in multistage shuttle and treadmill-run tests were sport dependent

St. James's University Hospital, Leeds - Recombinant bone morphogenetic protein is a safe bone-stimulating agent

St. Joseph Hospital, Bangor - Data advance knowledge in osteoporosis research

St. Jude Children's Hospital - Radiation dosimetry predicted IQ after CRT in pediatric patients with ependymoma

St. Vincent's Hospital, Darlinghurst - HIV-1 infection risk associated with SDF1 polymorphism and CXCR4 variation in South Africa

Starpharma - IND for prevention of HIV receives fast tracks status from U.S. FDA

Taipei Veterans General Hospital - Researchers describe findings in imaging studies

Teikyo University, Tokyo - Nitrogen accumulation during closed circuit anesthesia varies by surgery type

Thomson Scientific - Most cited researchers in clinical-medical journals listed in published study

TomoTherapy Incorporated - Imaging-radiation therapy system developer raises $14 million in private financing round

Transition Therapeutics Inc. - Drug development company completes $10,350,000 bought deal financing of common shares

Tufts University, Boston - Treatment with Neuroform self-expanding stent associated with mild in-stent restenosis

Tulane University, New Orleans - Centrally acting agents are the next targets for erectile dysfunction treatment

U.S. Department of Agriculture - Researchers have estimated the cost of E. coli O157 infections in U.S.

U.S. Food & Drug Administration - Study examined response of lipid bilayers and monolayers to trehalose

U.S. National Cancer Institute - An estrogen receptor chimera senses ligands by nuclear translocation

U.S. National Institutes of Health - Mutation that protects against HIV infection may raise risk of West Nile virus

Universitatsklinikum Essen - Transcription factor target genes identified in human embryonic kidney cells

Universitatsmedizin Berlin - New strategies help physicians make early diagnosis of spondyloarthritis

University Clinic of Munster - Cardiovascular assessment of systemic lupus erythematosus patients is recommended

University College London - Epirubicin/paclitaxel compared with epirubicin/cyclophosphamide in breast cancer

University Health Network, Toronto - New findings in the area of oncology described

University Hospital, Basel - Leaving internal thoracic artery perfused preserves endothelial function in arterial graft

University Hospital, Berlin - Aspirin and clopidogrel taken up to 2 days prior increase postoperative blood loss

University of Bologna - Implantable Coriolis force-based cardiac apex rotation monitor effective in sheep model

University of California, Davis - Flavanols in cocoa proven to benefit cardiovascular health

University of California, Davis - Researchers publish new studies and findings in the area of HIV/AIDS pathogenesis

University of California, San Diego - Alternative splicing database may facilitate splicing array design

University of California, San Francisco - Lack of 5-adrenoceptors results in enhanced insulin sensitivity mouse model

University of California, San Francisco - Positron-detecting probe used to localize recurrent melanoma intraoperatively

University of Florida - Method is developed to produce pseudotyped rAAV vectors using baculovirus expression system

University of Freiburg - Endothelial cell transplantation permits gene therapy in experimental gliomas

University of Illinois - Delaying surgery for hernia repair is a safe option for men

University of Iowa - Manganese superoxide dismutase modifies the expression of angiogenic growth factors

University of London Imperial College of Science & Technology - Interstitial cells from heart valves express various sarcomeric proteins

University of Maastricht - Cognitive therapy as good as physical rehabilitation for chronic lower back pain

University of Melbourne - GLUT1 and GLUT12 levels are raised in hypertension and diabetic nephropathy animal models

University of Miami - Incidence of prostate cancer progression after initial therapy reviewed

University of New South Wales - Predictors of posttraumatic stress disorder following cancer identified

University of Nice - Bioactive cyclic peroxides isolated from marine sponge Plakortis zyggompha

University of Otago, Dunedin - Watching television is an important factor in predicting childhood obesity

University of Rochester Medical Center - Influenza isn't the only germ threat in winter

University of Roma Tor Vergata - Recent findings in prostate cancer provide new insights

University of Sidney - Small benefits of endocrine therapy persuade some women to choose treatment

University of Technology Compiegne - Osteoblastic cells cultured in 3D microfluidic environment

University of Texas SW Medical Center, Dallas - Exogenous IL-7 may be of benefit during pathogenic SIVmac and HIV infection

University of Texas SW Medical Center, Dallas - Lumiracoxib treatment effective and well-tolerated

University of Toulouse 3 - Brain GLP-1 raises insulin secretion and muscle resistance to favor hepatic glycogen storage

University of Wisconsin - Signature domains of thrombospondin-4 and thrombospondin-2 are different

VU University, Amsterdam - Use of (18)FDG PET in patients with locally advanced non-small cell lung cancer assessed

VizX Labs - Gene expression analysis software company announces promotions, restructuring

Wake Forest University, Winston-Salem - Pediatricians should counsel children and their parents about UV protection

Xytis Inc. - Company raises $24.5 million in financing to conduct trials in CNS disorders, brain injury

ZARS Pharma - Robert Lippert named president and CEO of drug delivery-focused pharmaceutical company

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