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Aging Research

Reduced body temperature extends lifespan in mouse study from the Scripps Research Institute

Published in Healthcare Mergers, Acquisitions and Ventures Week, December 9th, 2006

Scientists at The Scripps Research Institute have found that reducing the core body temperature of mice extends their median lifespan by up to 20 percent. This is the first time that changes in body temperature have been shown to affect lifespan in warm-blooded animals.

The findings appear in a paper in the journal Science.

"Our study shows it is possible to increase lifespan in mice by modest but prolonged lowering of core body temperature," said Bruno Conti, an associate professor at Scripps Research who led the study. "This longer lifespan was attained independent of calorie restriction."

Prior to this study, researchers...

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