DNA Vaccines
Reports summarize DNA vaccines research from Merck & Co, Inc.
Published in Healthcare Mergers, Acquisitions and Ventures Week, February 17th, 2007
A report, "Identification and characterization of IS1 transposition in plasmid amplification mutants of E. coli clones producing DNA vaccines," is newly published data in Applied Microbiology and Biotechnology. According to recent research published in the journal Applied Microbiology and Biotechnology, "Merck Research Laboratories has developed a highly productive Escherichia coli fermentation process to produce plasmid DNA for use as vaccines. The process consists of a fed-batch fermentation in a chemically defined medium."
"Initiation of the feed stream precedes a growth-limited phase in which plasmid DNA is amplified. The fermentation is only maximally...
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