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Proteomics

Research from Xenome Ltd. has provided new data on proteomics

Published in Healthcare Mergers, Acquisitions and Ventures Week, March 17th, 2007

Investigators publish new data in the report "High-throughput synthesis of conopeptides: a safety-catch linker approach enabling disulfide formation in 96-well format." According to a study from Australia, "Conotoxins exhibit a high degree of selectivity and potency for a range of pharmacologically relevant targets. The rapid access to libraries of conotoxin analogues, containing multiple intramolecular disulfide bridges for use in drug development, can be a very labor intensive, multi-step task."

"This work describes a high-throughput method for the synthesis of cystine-bridged conopeptides.Peptides were assembled on a peptide synthesizer employing the Fmoc solid-phase...

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