Published in Healthcare Mergers, Acquisitions and Ventures Week, April 26th, 2008
"The RASGRP1/APTX gene expression ratio was found to predict response to tipifarnib with the greatest accuracy using a ''leave one out'' cross validation (LOOCV; 96%). RASGRP1 is a guanine nucleotide exchange factor that activates RAS, while APTX (aprataxin) is involved in DNA excision repair. The utility of this classifier for predicting...
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