Antibiotics
New findings from Technion in the area of antibiotics described
Published in Healthcare Mergers, Acquisitions and Ventures Week, September 26th, 2009
According to a study from Haifa, Israel, "We investigated the potency, selectivity, and mode of action of the oligo-acyl-lysine (OAK) NC12-2 beta(12), which was recently suggested to represent the shortest OAK sequence that retains nonhemolytic antibacterial properties. A growth inhibition assay against a panel of 48 bacterial strains confirmed that NC12-2 beta(12) exerted potent activity against gram-positive bacteria while exhibiting negligible hemolysis up to at least 100 times the MIC."
"Interestingly, NC12-2 beta(12) demonstrated a bacteriostatic mode of action, unlike previously described OAKs that were bactericidal and essentially active against gram-negative...
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