Published in Heart Disease Weekly, January 19th, 2003
"Prostaglandin E 1 (PGE-1) is a potent vasodilative agent which has been used to bridge patients with chronic heart failure listed for heart transplantation (HTX). In various experimental settings PGE-1 appears to stimulate angiogenesis by inducing vascular endothelial growth factor [VEGF] expression," wrote M.R. Mehrabi and colleagues.
To study PGE-1's angiogenic effects in such patients, the researchers studied "neovascularization ... in 14 explanted hearts from...
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