Heart Disease Weekly

Heart Disease Risk Factor - Insulin resistance may cause atherosclerosis in the postprandial period

Heart Failure - FDA approves digoxin, generic of Lanoxin

Heart Rate Variability - Detection of HRV phenotypes link to pathophysiology of autonomic nervous system

Heartbeat Regulation - Engineered calmodulins reveal the eminence of Ca²⁺ channel inactivation

Hypertension - Calcium-PKC system may play role in regulation of CNS cholinergic activity

Hypertension - Isoform-targeted regulation of cardiac adenylyl cyclase

Hypertension - Medications that normalize diurnal BP variation may improve CV prognosis

Hypertension - New enthusiasm for diuretics may be tempered by resistance problems

Hypertension - Researchers discover possible new mechanism

Hypertension - Statins regulate collagen I-dependent functions in vascular smooth muscle cells

Hypertension - Study: Boys born thin but heavy as teens have greater risk

Infective Endocarditis - More aggressive therapeutic approach needed to IE in high-risk patients

Intravascular Ultrasound - Coronary pulsation influences volumetric IVUS measurements without ECG gating

Ischemia - 5HD and diazoxide dangerous to use as modulators of mitoK_ATP channels

Ischemia - Heparinase improves collateral vessel development in the ischemic limb

Ischemia-Reperfusion Challenge - Creatine kinase activity is essential for full recovery

Ischemia/Reperfusion Injury - Reactive NO species trigger myocardial protection against reperfusion

Left Ventricular Mass - Gene-sex interactions regulate cardiomyocyte width and length independently

Magnetic Resonance Imaging - MR angiography with intra-arterial injections of contrast agents feasible

Molecular Medicine - Joint research initiative announced

Myocardial Infarction - Patient outcomes when living alone versus those not living alone are similar

Neurocardiogenic Syncope - Orthostatic self-training improves autonomic balance

Norepinephrine Efflux - Moderate hypothermia suppresses nonexocytotic release

Peripheral Adrenergic Function - Tyramine pressor tests measure of cardiac, not vascular, sympathetic function

Pulmonary Medicine - Systemic thrombolytic therapy after recent abdominal aortic aneurysm repair

Restenosis - Stent & delivery system to treat bifurcation lesions receives CE Mark approval

Senile Dementia Treatment - Acetylcholinesterase inhibitor reduces heart rate variability

Septic Shock - Hemodynamic effects of early versus late glucocorticosteroid administration

Sudden Unexpected Death Syndrome - New ECG criteria for high-risk Brugada syndrome

Surgical Adhesives - BioGlue effective in pituitary tumor surgery, heart VAD implantation

Thrombosis - CE mark awarded for mechanical thrombectomy device

Thrombosis - Extension of research funding granted on thrombin collaboration

Vasorelaxation - Evidence for additional mechanism underlying induction of acute vasorelaxation

Ventilatory Behavior - Nitric oxide mediates cardio-respiratory response to hypoxia

Ventricular Myocardium - Cantharidin delays endothelin-1- and carbachol-induced negative inotropic effect

Women's Health Diabetes - Researchers review obesity, diabetes, and coronary risk in women