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Heart Disease Weekly

Susan Hasty, Publisher

Table of Contents . . . October 19th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Heart Disease Weekly | Other Publications

Hypertension - New study shows why black males affected disproportionately

Open-Heart Surgery - Heart-stopping drugs described

Cardiology - Gene transfer of IkappaBalpha limits infarct size in a murine model

Coronary Artery Disease - Total plasma apoA-IV in coronary artery disease patients is lower than in controls

Sudden Cardiac Death - Researchers examine role of "hibernating myocardium" in major killer

Type 2 Diabetes Therapy - Brain natriuretic peptide predictive of left ventricular dysfunction

Acute Coronary Syndrome - Study: Early use of antiplatelet therapy reduces incidence of death

Adolescent Health - Study shows black girls retain more sodium when calcium intake is low

Alzheimer Disease - Haplotype block spanning IDE associated with risk and severity of disease

Angina - Low-dose aspirin is best choice for cutting bleeding risks

Aortic Aneurysm - Favorable preliminary findings reported for PowerLink pivotal clinical trial

Aortic Aneurysm - Uninsured face higher death risk from rupture

Atherosclerosis - Aspirin reduces risk of first heart attack by one-third

Atherosclerosis - Phospholipid transfer protein is expressed by macrophages in atherosclerosis

Cardiac Monitoring - Premarket notification filed with U.S. FDA for wireless EKG system

Cardiac Surgery - Cardiac surgery device manufacturer announces distribution agreements

Cardiac Surgery - Coronary artery bypass graft performing well in diabetic patient

Cardiology - Homeobox transcription factors may hold the key to groundbreaking therapies

Cardiology Training - Collaborative effort provides medical training for heart procedures

Cardiopulmonary Bypass - Heparin-induced thrombocytopenia is manageable in bypass surgery

Cardiovascular Disease - Study supports broad indications for PhotoPoint PDT in atherosclerosis

Cardiovascular Procedures - Device for percutaneous cardiovascular procedures receives FDA clearance

Carotid Stenting - Company initiates testing of TriActiv system in six carotid patients

Catheters - LifeValve Platinum, company's newest central venous catheter, launched

Childhood Disease - Babies exposed to Kingella kingae are susceptible to disease after 6 months

Collaborations - New firm to focus on next generation of drug-eluting stents

Congenital Heart Disease - FDA approves expanded label for Synagis use in children with CHD

Congestive Heart Failure - Can heart failure impair thinking?

Congestive Heart Failure - Respiratory pacing device found beneficial in heart failure

Coronary Lesions - Correlation found between lipid-rich plaques, heart attacks in cath lab patients

DNA Sequencing - Collaboration to focus on transformation of genome knowledge into health benefits

Defibrillators - Physio-Control and Laerdal defibrillators may be easier to use than the Zoll

Dementia - High blood pressure does not accelerate age-related cognitive decline

Dementia - High blood pressure is a factor in some "senior moments"

Dialysis - Company begins trial of noninvasive vascular blood clot treatment

Electrocardiography - Mobile electrocardiograph device now available to visiting nurse associations

Elevated Cholesterol - Crestor now available nationwide

Enzymology - VEGFR-2 responds to blood flow by mediating nitric oxide production

Finance - Cholesterol monitor company completes $3.35 million private placement

Fitness - Exercise program utilizing heart rate monitor shows fitness improvements

Fitness - Saying "yes" to regular physical activity says "no" to stroke

Genomics - Chemogenomics company's library now consists of more than 250 drug signatures

Graft Failure - Enrollment completed for pivotal phase III trial studying E2F Decoy

HIV/AIDS Therapy - HIV protease inhibitor can be co-administered with Maalox TC, Zantac, or Lipitor

Heart Disease Risk Factor - Reducing risk of congenital heart defects by vitamins debated

Heart Pump - Health Canada approves enhancements to Novacor LVAS

Hematology - Bleeding disorder in fawn-hooded hypertensive rat characterized

Hematology - Coagulation factor VIIa binds to tissue factor to prevent apoptosis

Hypertension - ALT-711 clinical development outlined

Hypertension - Improved diet, smoking cessation reduce blood pressure in African American women

Hypoxia - Activator protein-1 plays role in down-regulation of CYP2J2 gene in hypoxia

Immunology - Glycobiology company announces key appointments to board of directors

Information Technology - MedCath hires QuadraMed to implement clinical and financial information system

Kawasaki Disease - Pulmonary nodules with IgA plasma cells can occur in Kawasaki disease

Myocardial Infarction - Adjunctive therapy helps minimize damage to the heart

Myocardial Infarction - CORAL LAKE registry results presented

Myocardial Infarction - Study launched to identify patients in urgent need of defibrillators

Myocardial Infarction - Trial results demonstrate safety of endovascular cooling after heart attack

Pain Medicine - Severely preeclamptic patients have less hypotension during spinal anesthesia

Parasitology - Hormones and drugs that control blood pressure also control malaria

Pediatric Oncology - Childhood cancer survivors have increased risk for poor health as adults

Personnel - New members named to board of directors at medical device firm

Personnel - Pharmaceutical company appoints Nitin Kaushal to board of directors

Predictive Gene Function - Use of proteomics solutions demonstrated in cardiovascular disease

Prognostics - Treadmill test helps predict women's risk of death from cardiovascular disease

Proteomics - Migration inhibitory factor could be a therapeutic booster of cardiac repair

Quality of Care - Annual report card shows hospital care differs markedly among states

Restenosis - Positive phase II results in restenosis trial of Neugene

Restenosis - Resorbable polymer drug-delivery stent now visible by X-ray

Restenosis - Results presented on CDS-TC-32 in inhibition of restenosis

Restenosis - Safety and healing responses assessed in first coronary bioengineered stent

Stroke - Diabetes and hypertension combo invite silent stroke

Stroke - Survivin upregulation might generate therapeutic angiogenesis

Stroke Education - American Stroke Association partners to provide Internet-based stroke education

Sudden Cardiac Death - New risk factor first identified in Illinois family by SLU cardiologist

Thrombectomy - AKonya Eliminator mechanical thrombectomy device gets FDA clearance

Transfusion Complications - Transfusion-related acute lung injury is a risk factor for cardiac surgery

Vascular Occlusive Disease - Study demonstrates safety of acoustic energy on stented coronary arteries

Weight Gain - Postnatally overfed rats possess altered responses to neuropeptides

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