Coronary Artery Disease

Total plasma apoA-IV in coronary artery disease patients is lower than in controls

Published in Heart Disease Weekly, October 19th, 2003

ApoA-IV has three subfractions that do not differ, but the total of apoA-IV in plasma of coronary artery disease patients is lower.

According to recent research published in the Journal of Lipid Research, "Recent studies showed lower apolipoprotein A-IV (apoA-IV) plasma concentrations in patients with coronary artery disease (CAD). The actual distribution of the antiatherogenic apoA-IV in human plasma, however, is discussed controversially and it was never investigated in CAD patients. We therefore developed a gentle technique to separate the various apoA-IV containing plasma fractions.

"Using a combination of precipitation of all lipoproteins...

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Source: Heart Disease Weekly (2003-10-19)

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