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Heart Disease Weekly

Susan Hasty, Publisher

Table of Contents . . . April 25th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Heart Disease Weekly | Other Publications

Cardiology - Protein kinase C-alpha is a nodal integrator of cardiac contractility

Heart Disease Mortality - Combination of two common heart tests is strong predictor of death in patients

Angioplasty - Restenosis inhibited by tissue factor pathway inhibitor

Drug Development - Definitive Phase 1 QT ECG trial required for drug safety assessment

Heart Disease - PPAR-gamma role in cardiovascular disease reviewed

Acute Coronary Syndrome - Improved treatments needed to prevent restenting in diabetic patients

Angina - Status of percutaneous myocardial revascularization submission reported

Atherosclerosis - Lipoproteins inhibit cholesterol efflux to apolipoprotein A1

Atherosclerosis - Study: Eating walnuts improves endothelial function

Breast Cancer - Study says breast cancer survival improves if women stay active

Business & Finance - Company files 510(k) for its Atrilaze Soft Tissue Ablation System

Business & Finance - Medical device company announces sale of rotational thrombectomy technology

Business & Finance - Squalamine maker reports 2003 net loss of $12.5 million

Business Update - Genomics company "sharpens" focus, announces layoffs; CEO to retire

Business Update - Hydroxyapatite coating technology passes key systemic injection test

Cancer Therapy - Multimodality therapy for rectal cancer led to massive iliac artery bleeding

Cardiology - Simvastatin employs VEGF in the regeneration of arterial endothelial cells

Cardiology - Ultrasound-guided ablation eliminates an acardiac twin

Clinical Trial - Company awarded $1.2M for cardiac safety monitoring and services

Collaborations - Generex Biotechnology announces letter of intent for joint venture

Collaborations - NeoGenesis Pharmaceuticals announces drug-discovery collaboration

Collaborations - Sublicense granted to Roche Diagnostics for cardiac marker

Congestive Heart Failure - First MicroMed/DeBakey child ventricular assist device implanted

Coronary Artery Bypass - Desmopressin does not reduce postoperative bleeding in patients taking aspirin

Coronary Artery Disease - New growth factor protein helps damaged hearts

Coronary Artery Disease - Phase II trials initiated for pharmacologic stress agent for heart studies

Drug Development - Company reports advances in targeting Hypoxia-Inducible Factor

Finance - Biomaterials company receives $2.8 million through warrant exercise

Finance - Biopharmaceutical company announces sale of common stock

Finance - Blood-products company reports improved 2003 income

Finance - Medical device manufacturer completes extended share repurchase program

Finance - Valve maker reports revenue up 42% through third quarter fiscal year 2004

Forecast - Study: CerAxon will corner the neuroprotectant drug market in 2013

Genetic Disorder - Prevalence of hypercholesterolemia mutation in Quebec reported

Genetic Disorders - Umbilical and placental veins of babies with HHT1 thrive despite low endoglin

Genomic Biomarkers - Company contributes drug signatures to promote biomarker research

Healthcare Coverage - Program for chronically ill elderly patients cuts healthcare costs

Heart Attack - Blood-forming stem cells fail to repair heart muscle

Heart Attack - Cardiac device firm launches completely automatic AED

Heart Disease - Central Ohio hospital granted designation of Accredited Chest Pain Center

Heart Disease - Drug delivery firm completes trial for optimization of paclitaxel stent

Heart Disease Risk - New tool predicts and manages cardiovascular disease risk

Heart Disease Risk - Repeated treatment of gum disease reduces levels of inflammatory factors

Heart Disease Risk - Study questions value of inflammation test

Heart Disease Risk Factor - Signs of cerebral amyloid angiopathy-related inflammation reported

Heart Disease Therapy - Antarctic fish study may aid cardiac research

Heart Failure - Company reports preliminary results for EMOTE; doesn't reach primary endpoint

Heart Failure - Positive results reported in preclinical trial of Anginera

Heart Health - Research questions value of test to predict heart attacks

Heart Valve Prosthesis - Researchers develop a porcine model for a bileaflet heart valve prosthesis

Hematology - Central role of the P2Y12 receptor in platelet activation

Hypercholesterolemia - Moderate-intensity exercise does not reduce cholesterol

Hypertension - Primary endpoints met in PW2101 hypertension study

Hypertension Pathogenesis - Endothelin-1 plays role in regulating blood pressure in obese rats

Idiopathic Dilated Cardiomyopathy - Gene mutations that "ignore" stress lead to heart failure

Information Technology - Frankford Hospitals activate Sunrise Clinical Manager software solution

Kidney Disease - Swedish authorities approve FOSRENOL

Lipid Studies - Safflower phenolic compounds improve lipid profiles

Men's Health -  Harvard Heart Letter urges caution on testosterone therapy

Obesity Genomics and Genetics - Genetics of obesity in Mexican Americans explored

Organ Transplant - Clarian Health organ transplants rank fourth in nation

Patents - New nanobacteria patent announced

Personnel - Donahue named VP of cardiovascular marketing at biotech firm

Personnel - Thousands sign petition asking for reinstatement of Kentucky heart surgeon

Quality Assurance - Dramatic health gains predicted for Texas Medicare Demonstration Project

Quality Assurance - Software company receives ISO certification

Stents - Company expands Endeavor trial program in Europe

Stroke - Carotid stenting better at lowering cardiac risk in diabetics than surgery

Stroke - Consider tumor embolization in differential diagnosis of stroke after lung cancer surgery

Sudden Cardiac Death - Heartbeats warn of sudden death risk

Transplant Medicine - Babies can get hearts with wrong blood

Vascular Disease - One in four study participants at risk for abdominal aortic aneursym

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