Susan Hasty, Publisher
Table of Contents . . . October 17th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Heart Disease Weekly | Other Publications
Angiography - Study examines vascular complications after angiography and PCI
Angiology - Vascular dysfunction caused by oxidative stress is prevented by N-acetylcysteine
Echocardiography - ECG method provides a fast measure of LV volumes and reduces operator dependency
Myocardial Infarction - Findings support smaller, weight-adjusted dose of heparin for some patients
Renal Dysfunction - Renal dysfunction is associated with mortality in patients with heart failure
Abdominal Aortic Aneurysm - Changes in abdominal aortic aneurysm morphology occur after endovascular repair
Agriculture - Genetic modification of linseed produces healthier omega 3 and 6 fatty acids
Allergy Medicine - Agreement signed between pharma companies for allergy, hypertension medications
Angina - Inflammation markers signal rapidly advancing coronary disease
Angiology - Guinea-pig artery can be used to study side-effect potential of migraine drugs
Angiology - Low-risk participants had lower measurable coronary artery calcium later in life
Angiology - Review examines the vascular function of plasminogen activator inhibitor-1
Angiology - Study investigates monitoring of platelet function in preop clopidogrel delivery
Angiology - Study investigates the mechanism of the benefits of fish oil
Angiology - Superficial pseudoaneurysms are often mistaken for unrelated pathologies
Angiology - Two or three kiwi fruit per day reduced platelet aggregation response
Angiology - Vasoconstriction elicited by ergotamine is mediated by 5-HT1B receptors
Antibody Development - Antibodies acquired for use with SuperAntibody Technology platform
Anticoagulant Prophylaxis - Article reviews the epidemiology of venous thromboembolism
Anticoagulants - FDA committee wants more data to support approval of Exanta
Arthritis - VIOXX maker withdraws drug from market
Atherosclerosis - Certain common genetic polymorphisms affect response to atorvastatin
Atherosclerosis - Phenolic extracts from grape seeds, marc inhibit atherosclerosis in animal model
Atherosclerosis - VCAM-1, E-selectin, P-selectin levels are useful for detecting atherosclerosis
Atrial Fibrillation - Myocardial architecture confirmed initiating atrial fibrillation
Biosynthesis - Lipoxygenase pathways participate in progression of cardiovascular disease
Blood Vessel Growth - Scientists demonstrate multipotency of hair follicle stem cells
Business Update - Bayer enters strategic pharmaceuticals alliance
Business Update - Drug companies sign marketing agreement for antibiotic, erectile and other drugs
Cardiac Arrest - Catastrophic disruption in hearth rhythm focus of new search for markers
Cardiac Resynchronization - Left ventricular and biventricular pacing provide quantifiable benefits
Cardiac Safety Monitoring - ECG interpretation company wins $4.1M cardiac safety monitoring contract
Cardiology - 99mTc-CO-MIBI complex synthesized
Cardiology - ALK2 plays an essential role in the development of the cardiac outflow tract
Cardiology - Activation of myofibroblasts by TGF-beta1 may lead to valvular heart disease
Cardiology - Cardiac gene transfer improves myocardial blood flow locally
Cardiology - Echocardiographic features must be carefully defined
Cardiology - Genetic defect is required in neural crest cells and their migratory environment
Cardiology - H2 O2 attenuates Ca2+ accumulation during reoxygenation
Cardiology - Nav 1.5 can be ubiquitinated in heart tissues
Cardiology - Palivizumab epitope appears to be highly conserved
Cardiology - Report analyzes benefits of early thrombolytic therapy
Cardiology - Studies show relation between endothelial dysfunction and coronary events
Cardiology - Study investigates alterations of the autonomic nervous system
Cardiology - Study investigates the mechanism of myocardium protection
Cardiology - Unfractionated heparin will be replaced by better antithrombin agents
Cardiology - Vitamins E and C reduced heart damage caused by methidathion
Cardiology - [3H]mazindol binding is highly selective for norepinephrine transporters
Cardiovascular Devices - Temporal features of ICD-associated survival benefit characterized
Cardiovascular Disease - Alpha B-crystallin inhibits glucose-induced apoptosis in vascular cells
Cardiovascular Disease - Endovascular and treatment of vascular disease clinical trial results presented
Cardiovascular Disease - Nesiritide treatment associated with reduced in-hospital mortality
Cardiovascular Disease - Non-human primate study to research HDL Therapy in cardiovascular disease
Cardiovascular Disease - Research debunks myths about men's health
Cardiovascular Disease - Taurine validated as ischemic injury marker
Cardiovascular Diseases - PAI-1 exhibits unique conformational and functional properties
Cardiovascular Diseases - Screening athletes for conditions that risk sudden cardiac death is challenging
Cardiovascular Disorders - Crucial post-transcriptional events are regulated by chronic hypoxia
Cardiovascular Health - Evidence grows that drinking wine is beneficial for cardiac health
Cardiovascular Health - Review deals with the development of novel antiplatelet compounds.
Cardiovascular Health - Study reviews evidence for aspirin in treatment and prevention of CV disease
Cardiovascular Mortality - No link found between change in coronary heart disease mortality and infections
Cardiovascular Stents - HAp nano-film coating successfully completes safety studies
Cervical Cancer - Pharmaceutical company begins clinical trial for cervical cancer treatment
Chronic Renal Failure - Changing renal function confounds analysis
Chronic Respiratory Failure - Trial studies the effects of home pulmonary rehabilitation
Clinical Trials - Drug company awarded phase 1 study worth $1.5 million in cardiac services
Complementary & Alternative Medicine - Human clinical trial on green tea extract shows cholesterol-lowering effect
Congestive Heart Failure - Inhibition of Ca2+ efflux mode could improve contractility in heart failure
Congestive Heart Failure - Positive preliminary phase II results announced for Furosemide GR
Coronary Artery Bypass - Clinical study results announced for automated coronary anastomotic technology
Coronary Artery Bypass - Off-pump technique safe for second-time heart surgery patients
Coronary Artery Bypass Grafting - Non-invasive assessment of coronary artery bypass grafts reviewed
Coronary Artery Bypass Grafting - Quality of life comparable after initial and repeat CABG
Coronary Artery Disease - Osteoprotegerin gene polymorphisms associate with heart disease in men
Cystic Fibrosis - Companies agree to develop PEGylated secretin for cystic fibrosis
Deep Vein Thrombosis - Advocacy group supports release of updated guidelines for the prevention of DVT
Deep Vein Thrombosis - High prevalence of thrombophilic defects in spontaneous and effort-related UEDVT
Defibrillation - Body mass index is an independent predictor of defibrillation thresholds
Defibrillator - FDA clears HeartStart home defibrillator for over-the-counter sale
Developmental Biology - Analysis illustrates the mechanisms by which Hox genes orchestrate organogenesis
Diagnostics - Company announces latest statewide contract to provide remote ECG screening
Diagnostics - Licensing agreement to facilitate development of imaging agents for diagnostics
Diagnostics - Research shows treadmill test plus risk assessment helps predict mortality
Disease Management - More frequent monitoring advised for people with diabetes
Echocardiography - Hand-carried ECG had 100% sensitivity for detecting acute coronary syndrome
Echocardiography - Myocardial contrast ECG may be useful in routine post-AMI risk stratification
Echocardiography - Study salvaged nondiagnostic TTEs by using ultrasound contrast
End-Stage Renal Disease - Hypertension treatment in hemodialysis patients reviewed
Endocarditis - Half of patients 60 years of age warranted endocarditis prophylaxis
Endocrinology - Circulating mononuclear cells in the obese found to be in proinflammatory state
Epidemiology - Studies point to a pathophysiological basis for atherogenic potential of arsenic
Exercise Physiology - Physical conditioning blunts the effects of nitric oxide synthase deficiency
Finance - Biopharm reports year-end loss of $26 million
Finance - Cardiovascular and vascular device manufacturer reports record sales
Finance - Medical instrument company announces fourth quarter and year-end financials
Fitness & Wellness - Earlier diagnosis, education of heart patients may improve outcomes, poll shows
Fitness & Wellness - Home versions of health club fitness treadmills now available
Food Chemistry - Wild plants contribute to low incidence of atherosclerosis in Mediterranean area
Genomics - ABCA1 mutations have been identified in patients with HDL deficiency
Genomics - Researchers gathered to present completed sequences of three genomes
HIV/AIDS-Associated Disease - HIV-1 Tat increases adhesion of monocytes and T-cells to the endothelium
Healthcare Access - NewYork hospital launches $1 billion capital campaign
Heart Attack - First Washington-based Accredited Chest Pain Center announced
Heart Disease - First patient enrolled in trial of ZoMaxx drug-eluting coronary stent
Heart Disease - Pathogenesis of chronic Chagas disease is an unresolved issue
Heart Disease - Patient enrollment completed for ENDEAVOR III clinical trial
Heart Disease - Plasminogen may influence cardiovascular diseases in a number of ways
Heart Disease Prevention - Researchers find structure of enzyme giving red wine its beneficial properties
Heart Disease Risk - Abused, neglected children more likely to have heart disease as adults
Heart Disease Risk Factor - Coronary risk assessment varies in subjects with type 2 diabetes
Heart Failure - A-HeFT heart failure study added to ADA late-breaking plenary session
Heart Failure - InSync Sentry CRT-D approved for marketing in Canada
Heart Failure - PREDICT study results on heart failure released
Heart Transplantation - Artificial heart pilot trial enrolment completion announced
Heart Valves - Company announces first live implant of new BioPhysio heart valve
Hemodialysis - Disorders of mineral metabolism are associated with mortality in renal patients
Hemodynamic Physiology - Patients should be screened for CV, blood pressure disorders before liposuction
Hormone Replacement Therapy - Catecholamines may abrogate estradiol's antivasoocclusive effects
Hormone Replacement Therapy - E-2, but not phytoestrogen ZAL, directly affects cardiac contractile function
Hypercholesterolemia - Atorvastatin treatment suppressed CD40L and P-selectin expression
Hypercholesterolemia - Dense LDLs originate from two sources in cases of familial hypercholesterolemia
Hypercholesterolemia - Ezetimibe and atorvastatin together were well tolerated and efficacious
Hypercholesterolemia - Jaffa juice positively influences serum lipid, albumin, and fibrinogen levels
Hypercoagulability - Early diagnosis of hypercoagulability may allow pharmacologic intervention
Hypertension - A polymorphism of a gene encoding aldosterone may be linked to hypertension
Hypertension - Capsaicin increased the sensitivity of rat blood pressure to salt
Hypertension - Eurand inks agreement for development of lercanidipine
Hypertension - Increased pulse pressure may explain relation of CVD to systolic blood pressure
Hypertension - Results support recommendations for strict control of blood pressure
Hypertension - Sleep-disordered breathing plays a role in the development of hypertension
Hypothyroidism - Benefits of treating mild thyroid failure with L-thyroxine outweigh the risk
Imaging - Accurate method for interpretation of heart images developed in Finland
Imaging - Method corrects for heart motion by tracking the lung-myocardium interface
Imaging - PET method resamples heart images to a common model
Imaging - Patent announced for diagnostic ultrasound with microsphere imaging
Imaging - Technique maintains perfusion values and improves signal increase
Imaging - Visual analysis of contrast-enhanced-MR imaging studies can assess transmurality
Immunology - Celacade found to reduces cardiac muscle inflammation in preclinical study
In-Stent Restenosis - Impact of the use of sirolimus-eluting stents is evaluated
Information Technology - Comarketing agreement announced between risk management organizations
Information Technology - Sleep apnea council makes information from physicians available on website
Insulin - Insulin-delivery company has developed potential to convert a solitary tumor
Intracardiac Measurement - Mitral A-wave propagation velocity is age independent
Kidney Disease - Chronic kidney disease increases risk of heart disease, stroke, or death
Kidney Transplantation - Data presented on prevention of rejection after kidney transplantation
Lipid Studies - Antagonists of LPA receptors might help to prevent thrombus formation
Lipid Studies - Estradiol possesses a protective effect on the endothelium
Liver Transplantation - Researchers report on 18-year experience of liver transplantation
Lysophospholipids - Author raises questions about the role of lysophospholipids
Marfan Syndrome - Data support aneurysm surveillance and prophylactic surgical intervention
Market Analysis - Drug eluting stent utilization data released
Medical Devices - Cardiac monitoring and arrhythmia management service partners with Medtronic
Medical Devices - Electronics company launches branding campaign
Medical Devices - Imaging technology company releases device for 3-D view of coronary vessels
Medical Devices - Water, enclosures, and tool manufacturing company installs AEDs
Medical Equipment - Flat-panel detector used for cardiac studies and interventional procedures
Medical Facilities - All-digital heart hospital opens in Tulsa, Oklahoma, installs new IT system
Melioidosis - Researcher provide update on B. pseudomallei, "the great mimicker"
Myocardial Development - Differences in the origin of myocardia have implications for heart disease
Myocardial Infarction - Can we learn new tricks from an old drug in treating heart attacks?
Myocardial Infarction - Impairment of microcirculatory function may play a role in ballooning syndrome
Myocardial Infarction - Mitochondrial DNA polymorphism 5178A protects against heart attacks in Japan
Myocardial Infarction - Study documents biventricular reverse remodeling in patients with inferior AMI
Myocardial Infarction - Study evaluates the effect of melatonin on infarct size
Myocardial Infarction - U.S. heart attack patients survive longer than Canadians
Neuroscience - AT2 receptor is downregulated in post-MI ventricular remodelling in the rat
Neuroscience - Blocking of CRF1 receptors attenuates cardiovascular responses to stimuli
Obstetrics - Remifentanil effective anesthesia in parturients with critical aortic stenosis
Obstetrics - Tauroconjugated bile acid levels may be involved in obstetric cholestasis
Osteoporosis - Study suggests potential for vitamin D augmentation of estrogen therapy
Pediatric Obesity - Carotid artery thickening, stiffness found in obese children as young as 7
Pediatrics - Researchers find chronic illnesses among children not adequately addressed
Pericardial Effusion - Hand-carried cardiac ultrasound devices were used for bedside examination
Personnel - Dr. Burton Sobel joins board of alfimeprase maker
Personnel - New member appointed to medical device company's board of directors
Personnel - Pharma company announces addition of vice president of clinical pharmacology
Personnel - Pharmaceutical company names CFO and chief business officer
Plasmingen Activators - tPA participates in a number of events in the central nervous system
Platelet Inhibition - Prostaglandins can be used at lower concentrations to lower side effects
Protein Synthesis - Heparin dose-dependently modulates protein synthesis
Proteomics - Pharma company announces collaboration expansion with Kirin Brewery
Psychotropic Drugs - Licensing agreement for triple uptake inhibitors for depression clears hurdle
Research Publishing - Research spending and English proficiency are associated with publication output
Restenosis - Stent significantly reduces incidence of reblocked heart arteries in women
Sleep Apnea - FDA clears implantable medical device as treatment for sleep apnea
Sleep Apnea - Survey finds Americans don't recognize sleep as critical in maintaining health
Statin Therapy - The effect of statin therapy on NK cell cytotoxicity may contribute to benefits
Stem Cell Research - ESCs established from blastocysts differentiate into cardiomyoctes and neurons
Stem Cell Research - Economic study demonstrates Proposition 71 benefits to California's economy
Stem Cell Therapy - Embryonic SCs contribute to stable beneficial outcome in myocardial infarction
Stress - Anger, hostility, depression linked to high C-reactive protein levels
Survival & Mortality - Company announces two significant studies at HFSA meeting
Systemic Lupus Erythematosus - Disease activity is strongest risk factor for atherothrombosis in lupus
Thrombosis - Updated thrombosis guidelines offer recommendations
Transcutaneous Electrical Nerve Stimulation - TENS improves exercise tolerance and measures of ischemia but not symptoms
Transfection - The Sleeping Beauty transposon steers transgene expression
Vascular Disease - Strain from low aortic wall velocities in vivo can be quantified in vivo
Vascular Disease - Vascular repair and regeneration is regulated by bone-marrow derived cells
Vascular Occlusion - Monocyte chemoattractant protein-1 gene inhibition thwarts in-stent restenosis
Vasodilation - E-2 selectively boosts sensory nociceptor innervation of female rat arterioles
Vector Development - Adeno-associated viral vectors cultivate widespread muscle cell transduction
Ventricular Assist Devices - Global begins for VentrAssist artificial heart
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