Angiology
Vascular dysfunction caused by oxidative stress is prevented by N-acetylcysteine
Published in Heart Disease Weekly, October 17th, 2004
Investigators in Brazil report, "Vascular contraction and relaxation were determined in canine coronary arteries immersed in Kreb's solution (95% O2 -5% CO2 ), incubated or not with NAC (10 mM), and exposed to free radicals (FR) generated by xanthine oxidase (100 mU/ml) plus xanthine (0.1 mM). Rings not exposed to FR or NAC were used as controls."
A.J. Rodrigues and colleagues of the University of Sao Paulo explained, "The arteries were contracted with 2.5 mcM prostaglandin F2alpha. Subsequently,...
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Source: Heart Disease Weekly (2004-10-17)
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