Susan Hasty, Publisher
Table of Contents . . . November 7th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Heart Disease Weekly | Other Publications
Cardiac Devices - Biventricular ICDs offer survival benefit compared to biventricular pacing alone
Cardiac Devices - Thin filament is key modulator of contractile performance in failing human heart
Drug Therapy - Large study will evaluate n-3 polyunsaturated fatty acids and rosuvastatin
Heart Failure - The burden of heart failure is greater in ethnic minority populations
Ventricular Fibrillation - Radiofrequency ablation in children with Wolff-Parkinson-White syndrome studied
Abdominal Aortic Aneurysm - Estrogen protects male rats from aneurysm
Abdominal Aortic Aneurysm - FDA approves medical device to treat AAA
Abdominal Aortic Aneurysm - New technique to repair aneurysms safer
Adverse Drug Events - Study suggests caution against using certain drugs to unclog heart arteries
Alzheimer Disease - Pharma company's long-term study of Celebrex expected to continue
Amyotrophic Lateral Sclerosis - CytRx adds three drug candidates with acquisition of Biorex assets
Aneurysm - Company introduces low permeability AAA Device
Angiology - Human endothelial cells from different types of vasculature warrant study
Angiology - System may aid therapies to lower incidence of acute coronary artery diseases
Angioplasty - Augmented beta-endorphin is found in patients with coronary artery disease
Antiphospholipid Syndrome - Abnormal homocysteine metabolism not key factor in autoimmune disorder
Arrhythmias - FDA approves first U.S. implants of Philos II DR-T pacemaker
Arthritis - Research shows gelatine stimulates synthesis of type II collagen
Artificial Hearts - Company addresses possible reimbursement for VentrAssist LVAS
Atherosclerosis - Drug for rheumatism possible boon to heart patients
Atherosclerosis - MRI and spatially enhanced cluster analysis provide method to quantify plaque
Atherosclerosis - Results presented on antibody-based treatment of atherosclerosis
Atherosclerosis Vaccine - Cholesteryl ester transfer protein induces long-lasting antibodies
Atrial Fibrillation - Alcohol consumption may be associated with irregular heartbeat in men
Atrial Fibrillation - Anisotropic, decremental conduction occurs during onset of atrial fibrillation
Atrial Fibrillation - Asymptomatic atrial fibrillation after catheter ablation infrequent
Atrial Fibrillation - Biphasic cardioversion allows comparable success rates with lower energies
Atrial Fibrillation - Wave characteristics were repeatable from ECG to ECG for stable patients
Atrial Flutter - Beta-radiation can create linear lesions that are contiguous and nonthrombogenic
Atrial Tachycardia - Atrial hemodynamic burden is a determinant of sustained ANP response
Autonomic Nervous System - Colic infants do not have abnormal autonomic reactivity to stimuli while asleep
Bacteriology - Enterococcus faecalis fsr two-component system controls biofilm development
Bacteriology - Swedish company presents mass screening tests at investment conference
Bariatric Surgery - Obesity surgery can cure diabetes, high blood pressure and other ills
Blood Clotting Disorders - Gen-Probe signs licensing agreements
Breast Cancer - Study links low HDL levels with increased risk of postmenopausal breast cancer
Brugada Syndrome - Epicardial cooling could be an in vivo experimental model of Brugada syndrome
Business Update - Cardiology instrument designer and manufacturer added to Russell Indices
Business Update - Medical monitoring service changes stock symbol
Cancer Imaging Technology - Changes made to computed radiography system
Cardiac Anomalies - Toddler with uncommon condition showing improvement
Cardiac Arrest - Ephedrine linked to sudden cardiac death
Cardiac Devices - Long-term monitoring of SvO2 by implanted devices may be feasible
Cardiac Hypertrophy - Responses may influence cardiac performance during eccentric cardiac hypertrophy
Cardiac Monitors - FDA approves marketing a newly developed cardiac monitor
Cardiac Virus Detection - Real-time PCR is an efficient method to detect PVB19 infection in heart tissue
Cardiology - After initial damage, protective mechanisms within the heart were initiated
Cardiology - Columbus Regional Hospital receives Chest Pain Center accreditation
Cardiology - Correlation found between exhaled NO changes with exercise and peak VO2
Cardiology - Electroporation of hepatocyte growth factor DNA treats cardiomyopathy
Cardiology - Endogenous Ang II may modulate inward calcium current in the failing heart
Cardiology - European pharmaceutical awards $1.3M for electrocardiographic services
Cardiology - Heart rate, load effects on viscoelastic properties studied in animal model
Cardiology - LV systolic dysfunction was a strong predictor of mortality and morbidity
Cardiology - New catheter available for crossing chronic total occlusions
Cardiology - New treatment may help prevent blood clots
Cardiomyopathy - P-wave dispersion was higher in patients with dilated cardiomyopathy
Cardiovascular Disease - Biopharmaceutical company announces CARE 2 study
Cardiovascular Disease - Biosciences company enters collaboration to study genetics of heart disease
Cardiovascular Disease - Data on Thelin presented at American College of Rheumatology Meeting
Cardiovascular Disease - Decline in subarachnoid hemorrhage mortality is different in men than in women
Cardiovascular Disease - Prospective cohort study of the MONICA population published in Circulation
Cholesterol - Cholesterol guidelines become a morality play about conflict of interest
Cholesterol - New drug designed to reduce cholesterol levels launched
Congestive Heart Failure - Questionnaire is sensible and valid for estimation of daily energy expenditure
Congestive Heart Failure - Sinus node remodeling is characterized by reduced functional sinus node reserve
Coronary Artery Bypass Grafting - Fasudil attenuates post-CABG coronary artery spasm
Coronary Artery Bypass Grafting - Pericardial/serum myoglobin ratio may mark perioperative myocardial infarction
Coronary Artery Disease - 3-D fusion imaging is useful in decisions about coronary artery disease
Coronary Artery Disease - Ascending aortic BP waveform may be related to CAD risk in women, but not men
Coronary Artery Disease - Pharma company releases phase 1 results for coronary atherosclerosis treatment
Cystic Fibrosis - Company announces final research report on cystic fibrosis treatment
Diabetic Ketoacidosis - Cardiac troponin I concentration increases in diabetic ketoacidosis
Diabetic Nephropathy - Therapies for ventricular hypertrophy compared in diabetic patients
Diabetic Nephropathy - Treating albuminuria may prevent heart disease in diabetic patients
Diagnostics - Life sciences company announces Nanobacteria blood test manufacturing agreement
Disease Management - Program improved management of patients hospitalized for heart failure
Drug Development - Sense oligonucleotides targeting VEGF may help patients with ischemic tissues
Drug Development - Thelin for vascular constriction promising in patients failing bosentan therapy
Drug Therapy - A number of agents can modulate the expression of CD40 ligand
Drug Therapy - Levosimendan activates potassium flux to the mitochondrial matrix
Drug Therapy - Tezosentan at 1-25 mg/h improves hemodynamics and reduces B natriuretic peptide
Drug Therapy - Ventricular function and NYHA class, rather than age, predict low tolerability
Echocardiography - 3D echocardiography can aid selecting a pacing site in resynchronization therapy
Electrocardiography - Estimates of sensitivity and specificity varied greatly in individual studies
Embryonic Development - Connexin expression maintains lens quality and heart function in embryogenesis
Finance - Biotherapeutics announces third-quarter 2004 results
Fitness & Wellness - Medical device company introduces Premium Pedometer
Fitness & Wellness - Online survey shows restaurants struggling to keep dieting customers
Fitness & Wellness - Seapoint Farms introduces dry roasted edamame
Flavonoids - Artichoke flavonoids may represent the ingredients mediating eNOS up-regulation
Flavonoids - Grape seed flavonoids have exhibited antioxidant activity in a number of studies
Generic Drugs - Pharma company makes recommendation for usage of generic Vioxx
Genomics - Deoxyribozymes exhibit the ability to silence disease-associated genes
Gerontology Research - Mitochondrial damage may be associated with depleted CoQ and alpha-tocopherol
HIV/AIDS Therapy - Jury is still out regarding benefits of switching to protease-sparing regimen
HIV/AIDS Therapy - Nevirapine is better than efavirenz at raising "good" cholesterol
Heart Devices - 3F Aortic Bioprosthesis heart valve gets CE mark of conformity
Heart Disease - Canadian biotech company begins two studies on cholesterol combination therapy
Heart Disease - ChromoFlex heart stent receives European medical device approval
Heart Disease - Clinical trials slated for choelsterol drug
Heart Disease - Guidant to initiate vulnerable plaque study
Heart Disease Prevention - American Heart Association urges heart education
Heart Rate Variability - Short-term heart rate variability depended upon the type of exercise
Hormone Replacement Therapy - New guidelines confirm clinical value HRT for menopausal symptoms
Hormone Replacement Therapy - Short-term HRT effects vary among vascular sites
Hypercholesterolemia - MRI can measure early benefits of cholesterol-lowering drugs, plaque reduction
Hypertension - Captopril and L-arginine affect ventilation through different mechanisms
Hypertension - Folate intake lowers women's risk of high blood pressure
Hypertension - Insulin resistance in teens raises high blood pressure risk as adults
Hypertension - Left ventricular mass does not increase if BP is controlled for a long period
Hypertension - Stanford to test effects of drug widely used for pediatric hypertension
ICU Shock - B-type natriuretic peptides may provide useful information in ICU shock
Imaging - 23Na MRI may be a good technique for imaging nonviable myocardium in humans
Imaging - Colorado medical imaging group introduces preventive imaging screening services
Imaging - MRI technique is a reliable method for assessing deposition of iron in the liver
Imaging - Mn2+ ions, ion-releasing contrast media are effective for T1 imaging
Imaging - Study reports on automated quantification SPELT myocardial perfusion images
Inflammatory Reaction - VEGF is a key mediator of angiotensin II-induced vascular inflammation
Information Technology - Data exchange network launched for cardiology monitoring
Ischemia - Ischemia-modified albumin can be affected by skeletal muscle ischemia
Ischemia/Reperfusion - p38 and JNK prevent or promote cell survival in response to SI/R-induced injury
Ischemic Heart Disease - COX-2 inhibition in patients with ischemic heart disease merits investigation
Legal Issues - Implantable chip provides medical information, privacy worries
MR Angiography - Free-breathing navigator-gated method was superior in coronary MR angiography
Macular Degeneration - Pharma company announces data for ocular disorders trial
Medical Devices - Carotid stenting with emboli protection filter in high-risk patients studied
Medical Devices - Electronics company announces partnership, 500th installation of CardioMD
Medical Devices - Heart devices manufacturer comments on increased Medicare reimbursement for VADs
Medical Devices - Laser products utilized during live case sessions at transcatheter convention
Medical Devices - Sensing technology company chooses manufacturer for mobile vital signs system
Mergers & Acquisitions - Medical device company announces completion of Irvine Biomedical acquisition
Myocardial Infarction - Classification could be used to predict LV function at the time of discharge
Myocardial Infarction - Infarct size is a major determinant of high N-BNP levels
Myocardial Infarction - Mild exercise training ensured a beneficial role in the remodeling of the heart
Myocardial Infarction - Simple blood test for kidney function predicts heart attack death
Myocardial Infarction - Spanish trial suggests angioplasty after anticlotting therapy safe, beneficial
Myocardial Ischemia - Slow coronary flow alone may lead to myocardial ischemia
Myocardial Ischemia-Reperfusion - CAPE reduces size of I/R-induced myocardial infarction in rats
Myocardial Perfusion - Semiquantitative parameters have varied sensitivities for perfusion deficits
Natriuretic Peptides - Current assays require refinement
Nutrition - ConsumerLab.com approves Eskimo-3 in testing process
Nutrition - High intake of folates and vitamin B6 is inversely associated with MI risk
Nutrition - Olive consumption contributes to the benefits of the Mediterranean diet
Nutrition - Research shows omega-3 fats benefit cardiovascular health
Nutrition & Exercise - Effects of high-fat diet are prevented or reversed with exercise training
Obesity - America finally holds line on weight, market survey says
Obesity - Company wins phase I SBIR grant for obesity program
Obesity - Study finds nearly 200 million Chinese are overweight
Obesity Surgery - Surgical treatment for obesity appears effective for weight loss
Obstetrics - Tocolysis with beta-mimetic agent normalizes CTG pattern in early labor
Open Heart Surgery - Single postoperative measurement can estimate myocardial cell injury
Opthalmology - Treatment for wet age-related macular degeneration receives new brand name
Orthostatic Tolerance - Packed cell volume is important in determining orthostatic tolerance
Patient Information - Educational website for transmyocardial revascularization launched
Peripheral Arterial Disease - Angiogenesis therapy successful for artery disease
Personnel - Cancer diagnostic company announces new research and development executive
Personnel - Cardiovascular-focused biopharma appoints new CFO
Personnel - Dr. H. William Strauss named chairman of scientific and medical advisory board
Personnel - Drug delivery company appoints nonexecutive directors to the board
Personnel - Gary O. Tegan joins device maker as VP, marketing
Pharmacology - Myosin ATPase inhibitor activates ion channels and Ca2+-handling proteins
Rehabilitation - Shorter rehab stays may be linked with higher death rates
Restenosis - Thirty-day safety data reported from Taxus V drug-eluting stent clinical trial
Sleep Apnea - Study of association between APOE and sleep apnea reveals age dependency
Smoking Ban - Minnesota County approves new restrictions on smoking
Sports Medicine - Augmented metabolic stress was observed when strenuous exercise was repeated
Stem Cell Research - IFATS researchers believe fat stem cells may offer therapeutic potential
Stem Cell Research - Survey shows 3 in 4 Americans support Nancy Reagan's call for stem cell research
Stroke - Infection caused by periodontal pathogens is associated with future stroke
Stroke - Neurologic improvement a week after a stroke indicates later deterioration
Surgical Devices - Results of new heart surgery system discussed at conference
Thermoregulation - Moderate exercise in the cold while hypohydrated does not alter heat production
Thrombolysis - Effect of early vs. late prehospital thrombolysis studied in acute MI
Tissue Engineering - Scaffold topography alters cardiomyocyte network intracellular calcium dynamics
Transfusion Medicine - Reconstituted blood is better for infants' heart surgery than fresh blood
Transplant Medicine - Wisconsin boy receives new internal heart pump for children
Vagal Dysfunction - Stimulation with pyridostigmine may be a therapy option for vagal dysfunction
Vascular Disease - Reduced plasma glutathione levels are a risk factor for cardiovascular disease
Vascular Noradrenaline Sensitivity - Mechanisms may contribute to the protective actions of AT1 blockers
Vitamin Therapy - Vitamin treatment may reduce cardiovascular morbidity and mortality
Wilms Tumor - Evidence that therapy with doxorubicin improves survival remains elusive
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