Embryonic Development
Connexin expression maintains lens quality and heart function in embryogenesis
Published in Heart Disease Weekly, November 7th, 2004
"Gap junctions are composed of connexin (Cx) proteins and mediate intercellular communication required for many developmental and physiological processes. Here we describe the isolation and characterization of Cx48.5, a zebrafish connexin with the highest sequence identity to mammalian Cx46," researchers in Canada report.
"Expression analysis showed that Cx48.5 is expressed in the adult and embryonic lens and heart, adult testis, and transiently in the embryonic otic vesicles. Injection of Cx48.5 cRNA into Xenopus oocytes elicited intercellular electrical coupling...
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Source: Heart Disease Weekly (2004-11-07)
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