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Myocardial Infarction

A change in myoglobin provides an accurate diagnosis of acute MI

Published in Heart Disease Weekly, December 26th, 2004

Researchers have investigated the use of a change in serum myoglobin to detect acute myocardial infarction in patients with normal troponin I levels.

Investigators in the United States report, "We sought to determine the sensitivity of a change in myoglobin for acute myocardial infarction (AMI) in patients who had normal levels of troponin I at presentation. Myoglobin increases as soon as 1 to 2 hours after symptom onset in AMI. The change in myoglobin may help identify AMI in patients with normal cardiac levels of troponin I on admission."

S.M. Sallach and colleagues of the University of Texas described their study, "A total of 817 consecutive...

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