Published in Heart Disease Weekly, December 26th, 2004
"A series of 11C-labeled analogs" of the AChE inhibitor "pyridostigmine have been synthesized for evaluation as new potential positron emission tomography (PET) imaging agents for heart AChE."
"The appropriate precursors for radiolabeling were slightly modified from commercial reagents," explained J.Q. Wang and coauthors at Indiana University. "The new tracers [11C]pyridostigmine (1), [11C]para-pyridostigmine (2) and [11C]ortho-pyridostigmine (3) were prepared by N-[11C]methylation of the...
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