Heart Disease Weekly
Susan Hasty, Publisher
Table of Contents . . . April 24th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Heart Disease Weekly | Other Publications
Cardiology - Abnormal wall motion may be a stimulus for matrix metalloproteinase activation
Cardiology - Determinants of coronary flow are determined by different physiological factors
Cardiology - ECG is the only consistent diagnostic tool for AMI trends over 25 years
Congestive Heart Failure - Article reviews techniques for calculating lifetime benefit of HF intervention
Heart Failure - Beta-blocker therapy with bucindolol may attenuate risk of MI in HF patients
Acute Myocardial Infarction - Access-site complications limited after rescue PCI during thrombolysis
Adverse Drug Reaction - Researchers identify possible risk associated with commonly used heart drug
Anesthesia - Heart disease can be a significant issue in Williams syndrome
Anesthetics - Anesthetics have enantioselective actions on coronary resistance vessels
Angiology - Arterial matrix components studied, involvement in synthase inhibition shown
Angiology - Diseases impairing ventricular relaxation may retard flow propagation velocity
Atherosclerosis - Recent findings in atherosclerosis described
Angiology - For detecting abnormal motion, increasing frames from 8 to 16 holds no advantage
Angiology - NT-pro-BNP concentrations are high across spectrum of coronary artery disease
Angiology - New test measures platelet, coagulation risk factor before thrombotic event
Angiology - Researchers publish new studies and findings in the area of angiology
Angiology - Vascular effects of cytokines depend on balance between vasoactive mediators
Angiotensin - Angiotensin II examined, nature of matrix metalloproteinase induction revealed
Cardiology - Researchers describe findings in cardiology studies
Apoptosis - Beta2 -glycoprotein I examined, apoptosis protective roles revealed
Arteriopathy - Pulsatility index linked to arteriopathy grade in type 2 diabetics
Atherosclerosis - Family propensity to atherosclerosis interacts with metabolic risk factors
Atherosclerosis - New findings in atherosclerosis described
Atherosclerosis - T-bet deficiency studied, effects on atherosclerosis and immune responses shown
Cardiology - Researchers' data advance cardiology research
Atrial Fibrillation - Transesophageal ECG detects thromboembolism risk markers in patients with LAF
Balloon Aortic Valvuloplasty - Antegrade transseptal approach improves outcome of percutaneous BAV
Biometeorology - Study evaluated association between meteorological conditions and sports deaths
Blood Pressure - Ambulatory BP monitoring may be used to optimize heart failure therapy
Blood Pressure - Cardiac hypertrophy and dysfunction studied, role of blood pressure revealed
Business Update - Biotech company completes first stage of RFP process with pharma organizations
Cardiology - Researchers' work adds to cardiology body of knowledge
Business Update - Company launches FloTrac in Europe
Business Update - Report shows surgeries on rise, increasing use of outpatient, same-day surgery
Business Update - U.S. FDA approves sterilization site for microsurgical dilation device
Cardiac Catheterization - Supplemental oxygen increases vascular resistance in cardiac catheterization
Cardiac Development - Early coronary formation starts in the inner curvature
Cardiac Development - Loss-of-function data question dominance of GATA-4 during heart development
Cardiac Failure - Two forms of heart failure occur in obese patients
Cardiac Hypertrophy - Researchers publish new studies and findings in the area of cardiac hypertrophy
Cardiology - Aroylhydrazones merit investigation as protective agents against cardiotoxicity
Cardiology - CGRP mediates cardioprotective effects of remote preconditioning
Cardiology - Cardiac K+ channel analyzed, Ca2+ influence clarified
Cardiology - Cardiac bedside monitor-defibrillator versus code blue protocol to be studied
Cardiology - Cardiac cycle may time blood delivery to legs when muscular pressure is lower
Cardiology - Cardiac neural crest influences the development of myocardial Ca2+ channels
Cardiology - Government grant to expedite development of stent coating awarded
Cardiology - Hepatitis C virus core protein produces heart disease in transgenic mice
Cardiology - Impaired myocardial relaxation is determinant of PVP only during rapid HR
Cardiology - Left atrial dimension was associated with presence of coronary artery calcium
Cardiology - MCFA supplementation improves capacity to withstand an acute adrenergic stress
Cardiology - Matrix metalloproteinases examined, fibroblast activation systems identified
Cardiology - Plasma mitochondrial coupling factor in acute myocardial infarction revealed
Cardiology - Protective effect of remote preconditioning is memorized in the explanted heart
Cardiology - Regulator of G-protein Signaling 5 (RGS5) is up-regulated in atria of TG4 mice
Cardiology - Reports describe recent advances in cardiology research
Cardiology - Rhythm-control strategy should be considered for patients with high IRVR
Cardiology - Salusins induce hypotension via negative inotropic and chronotropic actions
Cardiology - Short photoperiods may reprogram function of the cardiac sarcoplasmic reticulum
Cardiology - Sodium-calcium exchanger protein undergoes rapid turnover in cardiac cells
Cardiology - Study investigated cardiac index decreases observed during portal triad clamping
Cardiology - Technique offers potential for exploring microcirculation regulation in vivo
Cardiology - U.S. clinical trial of AngioSculpt completed
Cardiomyocytes - CGRP acts differently on developing cardiomyocytes than on developed ones
Cardiomyocytes - Study examined diminished effects of NO and CNP on myocyte contraction
Cardiomyopathy - Regular cardiac evaluation should be routine for mucopolysaccharidoses patients
Cardioprotection - Blocking MPT pore opening is key process in NO donor-induced cardioprotection
Cardioprotection - Proanthocyanidins have attracted attention as cardioprotective compounds
Cardioprotection - Tolerance to cardioprotection allows protection by different signaling pathways
Cardiovascular Devices - LVAD implantation in patient with dextrocardia reported
Cardiovascular Disease - Activators of PPARs may be therapeutic agents in preventing CV disease
Cardiovascular Disease - Antioxidant effects likely contribute to the clinical efficacy of statins
Cardiovascular Disease - Geomagnetic field variations insignificantly affect incidence of CV disease
Cardiovascular Disease - Oxidative stress is a factor in pathogenesis and progression of CV disease
Cardiovascular Disease - Periodontal disease may contribute to the pathogenesis of cardiovascular disease
Cardiovascular Disease - Report provides overview of mechanisms causing endothelial dysfunction
Cardiovascular Disease - Women who've had hysterectomy have more CVD risk factors
Cardiovascular Disease Risks - Anxiety, depression associated with unhealthy lifestyle in patients at risk CVD
Cardiovascular Diseases - Patients with low ankle-brachial index have increased risk of mortality
Cardiovascular Research - Adrenomedullin improves cardiac function in rodents treated for infarction
Cardiovascular Research - Article aims to increase sonographer awareness of research grant opportunities
Cardiovascular Research - Dynamic interactions might have roles in regulating CV function during hypoxia
Cardiovascular Research - Exercise-induced inferior ischemia activates the cardioinhibitory reflex
Cardiovascular Research - GTPCH-I activity in CV system may be a mechanism that regulates BH4 levels
Cardiovascular Research - Hibernators may use up-regulation of proteins to counteract oxidative stress
Cardiovascular Research - Signal prediction error can represent a resting physiologic system
Cardiovascular Research - Study examined effects of acupuncture on CV responses to gastric distension
Cardiovascular Research - Study investigated CV autonomic control of endurance-trained female athletes
Cardiovascular Research - Study investigated the mediation of estrogen effects on the CV system
Cardiovascular Risk Factors - Weight is an important factor in vascular aging in mid-life women
Cell Biology - Yeast finding links processes in heart disease and cancer
Clinical Trials - Enrollment begun for embolic protection device in carotid clinical trial
Collaborations - Curis achieves milestone
Collaborations - Deal signed to extend paclitaxel technology into coronary bypass surgery
Collaborations - Pharma companies announce drug discovery and development collaboration
Colon Cancer - Pharma company gives results of investigational drug study in colon cancer
Colorectal Cancer Therapy - Hepatic arterial infusion not advised after resection of colorectal cancer
Complementary & Alternative Medicine - Omega-3 fish oil infused with plant phytosterols said to reduce cholesterol
Congestive Heart Failure - Heart assist device company files for CE Mark approval to market LVAS in Europe
Congestive Heart Failure - Researchers search for first sign of failing heart
Congestive Heart Failure - Venilator efficiency improved by monosaccharide
Constrictive Pericarditis - Doppler imaging offers diagnostic information in constrictive pericarditis
Coronary Artery Bypass - Trial of drug for preventing coronary artery bypass graft failure initiated
Coronary Artery Bypass Grafting - CT suitable for imaging of nitinol implant-induced proximal anastomosis
Coronary Artery Bypass Surgery - Sevoflurane preserved myocardial function better than propofol in bypass surgery
Coronary Artery Disease - Benefits of black tea consumption may not be attributable to tea catechins
Coronary Artery Disease - Cardiac practices lack guidelines for managing psychosocial risk factors
Coronary Artery Disease - Free plasma oxysterol levels may be important atherogenic risk factors
Coronary Artery Disease - Oxidative stress may be responsible for accumulation of mtDNA damage in CAD
Coronary Artery Disease - Tryptase measurements may be a way to identify asymptomatic patients with CAD
Corticotropin-Releasing Factors - Corticotropin-releasing factor receptor studied, ligand binding revealed
Diabetes Complications - I-to remodeling in diabetic rat heart is due to decreased TRX reductase
Diabetes Complications - Non-linear measurement of HRV distinguishes cardiac dysregulation
Diabetes Control - Angiotensin II receptor blockade protects heart from effects of diabetes
Diabetes Pathogenesis - Findings advance knowledge in diabetes pathogenesis research
Diabetic Complications - Diabetic rats respond differently to magnesium than do controls
Diagnostics - Multi-center study on cardiac imaging system ready for patient evaluations
Diagnostics - U.S. FDA grants approval to market cardiology device
Diet & Nutrition - Compound in broccoli sprouts found to be disease fighter
Diet & Nutrition - Magnesium helps minimize Ang II-induced myocardial complications
Disease Associations - Cigarette-induced endothelial apoptosis examined, nitric oxide protection noted
Disease Associations - Parkinson disease analyzed, profound cardiac sympathetic denervation observed
Drug Delivery - Infusion system studied in patients with CKD undergoing heart procedures
Echocardiography - Anatomical M-mode ECG can be used instead of left atrial appendage area change
Echocardiography - Imaging with radionuclide tracers is used to identify viable myocardium
Echocardiography - RTI and TRI are equivalent to SPECT in detecting diseased artery territories
Echocardiography - Second harmonic TTE can provide valuable information about left atrial appendage
Echocardiography - TTE and TEE are imaging procedures of choice for diagnosing cardiac hydatid cyst
Electrocardiography - Model addresses problem of fetal ECG extraction using BSS in the wavelet domain
Embryonic Stem Cell Research - Embryonic stem cells are a source of dendritic cells for clinical applications
Fatty Liver Disease - Statins not guilty of hepatotoxicity
Finance - Defibrillator maker files 2004 Form 10-K
Finance - Technology company reports first quarter 2005 results
Finance - Tennessee-based branded pharmaceutical company reports Q4, year end 2004 results
Genetics & Genomics - Mixed effects models provide a flexible framework for studying gene interactions
Genistein - Genistein analyzed, differential action in ventricular myocardium revealed
HIV/AIDS-Related Metabolic Syndrome - Lipid-lowering drugs may cause pharmacokinetic interactions with antiretrovirals
Healthcare Disparity - Cardiologists underestimate racial and ethnic disparities in care
Heart Disease - Twin-to-twin transfusion syndrome presents an increased risk of adult disease
Heart Failure - Improvement needed in delivery of care to hospitalized heart failure patients
Heart Failure - Medical technology company announces catheter set for heart failure
Heart Failure - Studies may provide mechanistic explanation for effects of carvedilol in HF
Heart Failure - Web site explains trial testing heart failure medication in African-Americans
Heart Surgery - New marker for early diagnosis of kidney failure identified
Heart Transplantation - Perioperative management of pediatric patients reviewed
Heart Transplantation - Recombinant FVII used to control bleeding during RVAD implantation
Hematology - Stimulation of platelet production may provide a new management option for ITP
Hormone Replacement Therapy - Estradiol affects blood pressure response to orthostasis in healthy older women
Hypercholesterolemia - Study reveals potential new target for cholesterol-lowering drugs
Hypercholesterolemia - Take heart, it's all good news
Hypertension - AHA makes recommendations on blood pressure measurements
Hypertension - Acupuncture found to lower elevations in blood pressure
Hypertension - Asymptomatic LVSD is a potent and early marker of evolution toward severe CHF
Hypertension - Current management of hypertension is based on extensive published literature
Hypertension - Exercise testing can be performed safely in children with pulmonary arterial HT
Hypertension - Five percent less body weight reduces obese women's blood pressure
Hypertension - Hypoxia-induced pulmonary hypertension causes changes in pulmonary vasculature
Hypertension - Improved blood pressure control measures recommended for middle-aged in China
Hypertension - Waist circumference accounts for various factors' link to blood pressure
Hypertension Therapy - Dihydropyridines have differential effects on alpha1G calcium channels
Hypertrophic Cardiomyopathy - Short-term method may be sufficient to assess HRV in patients with HCM
Hypertrophic Cardiomyopathy - Variability in pCa50 may be primary cause for contractile dysfunction
Hypertrophy - Knowledge of NO-cGMP counter-regulatory system will offer treatment strategies
Hypoxia - Hypoxic syncope results from superimposed vasodilator effects on the CV system
Hypoxia - Limbic structures participate in responding to hypoxic challenges
Idiopathic Pulmonary Fibrosis - Volunteers needed for university study of idiopathic pulmonary fibrosis
Imaging - 16-slice MSCT is useful for noninvasive exclusion of coronary artery disease
Imaging - California hospital updates cath lab with new 3D soft-tissue imaging technology
Imaging - Data advance knowledge in imaging research
Imaging - Scanner manufacturer proceeds with international cardiac CT study
Inflammation - Influenza infection studied, acute inflammatory state clarified
Ischemia - Study assessed the CV effects of Deltorphin-D-variant after hemorrhage
Kidney Disease - Mouse model reveals potential way to reduce cardiac deaths in kidney patients
Kidney Transplantation - Dialysis before renal transplantation causes detrimental changes in vasculature
Legal Issues - Maker of low perfusion pulse oximetry wins antitrust lawsuit against Tyco
Lipid Metabolism - ApoC-I synthesis and secretion studied, post-transcriptional regulation defined
Magnetic Resonance Imaging - DENSE MRI can assess 3D myocardial mechanics of the murine heart in <1 hour
Magnetic Resonance Imaging - Method offers noninvasive approach to longitudinal studies of cardiac disease
Magnetic Resonance Imaging - Real-time cine MRI may help to identify causes of impaired ventricular filling
Magnetic Resonance Imaging - Tube model used to calculate rf alteration caused by conductive implants
Medical Devices - Continuous noninvasive blood pressure monitoring system introduced
Medical Devices - Report describes probe for transesophageal ECG and transesophageal cardioversion
Medical Devices - Twenty-five year study of bileaflet prosthetic heart valve published
Mental Health - Depression is associated with a doubled risk of subsequent cardiac events
Mergers & Acquisitions - Acquisition agreement for developer of stroke prevention technology executed
Myocardial Dysfunction - Glowing hearts shine light on heart disease
Myocardial Infarction - Can donor adult stem cells repair muscle damage from heart attack?
Myocardial Infarction - Extreme exertion, emotion can spark repeat heart attacks
Myocardial Infarction - Imaging technique identifies vulnerable plaques in cardiac patients
Myocardial Infarction - Multipotent stem cells from bone marrow revitalize injured cardiac tissue
Myocardial Infarction - New findings in the area of myocardial infarction described
Myocardial Infarction - O2 consumption is similar to supply in remodeled myocardium during exercise
Myocardial Infarction - Reduced MLP-calcineurin signaling predisposes to adverse remodeling after MI
Neuroactive - Neuroactive peptide studied, intracerebroventricular infusion revealed
Nutrition - Dietary fatty acids ameliorate heightened inflammatory cytokines
Obstructive Sleep Apnea Syndrome - Obstructive sleep apnea impairs baroreflex gain and respiratory-CV coupling
Oncology - Researchers' data advance oncology research
Pain Management - Report: FDA's COX-2 recommendations will benefit Bextra and Celebrex
Patent Foramen Ovale - Treatment of cardiac lesions without anesthetic explored
Patents - Company awarded patent for vascular therapy
Peptide Receptors - D-VIP analyzed, effects on L-VIP-elicited vasodilation revealed
Percutaneous Coronary Intervention - Closure devices may increase vascular complication risk
Peripheral Arterial Disease - First U.S. drug-eluting stent trial to treat PAD enrolls first patient
Peripheral Arterial Disease - First drug-eluting stent implant for leg artery blockage performed at Stanford
Peripheral Arterial Disease - Low vitamin D, impaired bone turnover, and low bone mass are common in PAD
Personnel - Consulting physician joins LifeShirt makers scientific advisory board
Personnel - Pharmaceutical company names Jerry Okikawa senior director, product development
Physiology - Mesenteric resistance arteries studied, impaired flow-induced dilation revealed
Proteomics - PARP-1 may provide cardioprotection by regulating signal transduction pathways
Proteomics - cTnT1 expression levels during development can affect ventricular function
Pulmonary Arterial Hypertension - Ventavis commercially available for the treatment of PAH
Refractory Angina - FDA approves protocol amendments to GENASIS phase IIb clinical trial
Reperfusion - Post-reperfusion absorption studied, role of P-glycoprotein clarified
Respiratory Medicine - Compromised vascular remodeling contributes to pulmonary arterial hypertension
Restenosis - Company gets conditional IDE to begin COSTAR II pivotal clinical trial
Smooth Muscle - Matrix metalloproteinase expression studied, effect of pioglitazone defined
Statins - Effects of simvastatin are mediated through inhibition of endothelin-1
Statins - Researchers report details of new studies and findings in the area of statins
Statins - Simvastatin therapy improves LV systolic function and decreases repeat PCI rate
Stem Cell Research - ESC-derived atrial cardiomyocytes identified during early development
Surgical Technology - European clinical study of adhesion barrier for use in cardiac surgery initiated
Systemic Inflammatory Response Syndrome - CV abnormalities can be identified at bedside for pharmacologic management
Transplant Medicine - FK778 prolongs cardiac allograft survival
Transplant Medicine - Longest surviving artificial heart patient marks 5 years on miniature device
Venous Aneurysm - Correlation found between occurrence and female sex, high BMI in males
Weight Loss - Cutting calories cuts coronary heart disease risk
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