Published in Heart Disease Weekly, May 22nd, 2005
Study 1: A recent report describes inward-rectifier K+ current in guinea-pig ventricular myocytes exposed to hyperosmotic solutions.
According to a study from Canada, "Superfusion of heart cells with hyperosmotic solution causes cell shrinkage and inhibition of membrane ionic currents, including delayed-rectifer K+ currents. To determine whether osmotic shrinkage also inhibits inwardly-rectifying K+ current (IK1 ), guinea-pig ventricular myocytes in the perforated-patch or ruptured-patch configuration were...
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