Tissue Engineering
Endothelium directly cocultured on smooth muscle cells
Published in Heart Disease Weekly, June 19th, 2005
"The development of a functional, adherent endothelium is one of the major factors limiting the successful development of tissue engineered vascular grafts (TEVGs). The adhesion and function of endothelial cells (ECs) on smooth muscle cells (SMCs) are poorly understood.
"The goal of this research was to optimize conditions for the direct culture of endothelium on SMCs, and to develop an initial assessment of coculture on EC function," scientists in the United States report.
"The coculture consisted of a culture substrate, a basal adhesion protein, a layer of porcine SMCs,...
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Source: Heart Disease Weekly (2005-06-19)
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