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Aortic Valve Disease

Researchers link ACE inhibitor use with a lower rate of AVC accumulation

Published in Heart Disease Weekly, June 19th, 2005

Researchers at the University of Washington in the U.S. have linked angiotensin-converting enzyme inhibitor (ACEI) use with a lower rate of aortic value calcium (AVC) accumulation.

"Calcium accumulation in the aortic valve is a hallmark of aortic sclerosis and aortic stenosis. Because lipoproteins, angiotensin-converting enzyme, and angiotensin II colocalize with calcium in aortic valve lesions, we hypothesized an association between angiotensin-converting enzyme inhibitor (ACEI) use and lowered aortic valve calcium (AVC) accumulation, as measured by electron beam computed tomography," reported K.D. O'Brien and colleagues in a recent issue of the journal, Archives of...

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