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Anesthesia

Landiolol may help prevent tachycardia without affecting BP during anesthesia

Published in Heart Disease Weekly, June 26th, 2005

Landiolol attenuates tachycardia in response to endotracheal intubation without affecting blood pressure.

According to a study from Japan, "Beta-adrenergic receptor antagonists (beta-antagonists) have long been used to control perioperative tachyarrhythmias. The effects of a beta1 -antagonist, landiolol, on perioperative hemodynamics are unknown. We aimed to determine the appropriate dosage of landiolol for the treatment of hemodynamic changes in response to endotracheal intubation."

A. Yamazaki and colleagues of Wakayama Medical University explained, "Sixty-four patients without heart disease or hypertension, were assigned to receive...

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