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Diagnostics

Treatment with LMWH plus warfarin reduces accuracy of point-of-care INR testing

Published in Heart Disease Weekly, January 8th, 2006

The accuracy of point-of-care INR testing is reduced during treatment with low-molecular-weight heparin (LMWH) and warfarin.

In a "retrospective study", physicians in the United States compared "the international normalized ratio (INR) measured by a point-of-care testing device with that measured by a reference laboratory method for patients receiving either warfarin only" or warfarin plus LMWH.

"Ninety-one patients receiving warfarin for various indications" were enrolled, according to E.M. Phillips and coauthors at the State University of New York Upstate Medical University. Of the enrolled patients, 59 received "only warfarin" while 32 were...

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