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Hypertension

Exposure to a low-protein diet in utero spawns microvascular dysfunction

Published in Heart Disease Weekly, January 8th, 2006

Exposure to a low-protein diet in utero spawns microvascular dysfunction.

"In hypertension, increased peripheral vascular resistance results from vascular dysfunction with or without structural changes (vessel wall remodeling and/or microvascular rarefaction). Humans with lower birth weight exhibit evidence of vascular dysfunction," scientists in Canada report.

"The current studies were undertaken to investigate whether in utero programming of hypertension is associated with in vivo altered response and/or abnormal vascular structure. Offspring of Wistar dams fed a normal (CTRL) or low (LP)-protein diet during gestation were studied," wrote P. Pladys...

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