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Heart Disease Weekly

Susan Hasty, Publisher

Table of Contents . . . April 9th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Heart Disease Weekly | Other Publications

Cardiology - Wave fractionation mechanisms offer new perspective on atrial fibrillation

Imaging - Atherosclerosis imaging on the molecular level is work in progress

Ischemia - In ischemia-reperfusion injury, glutathionylated actin may contribute to changes in contractile function

Adverse Drug Reaction - U.S. FDA web site warns of risk of cardiovascular adverse reactions from methylphenidate

Agriculture - Monsanto recommits to adding new value to U.S. soybean production

Alzheimer Disease - Drug company reviews studies on potential of statin drugs to treat Alzheimer disease

Anesthesia - Angioplasty of lower limb is facilitated by use of regional nerve blockade

Anesthesia - Enhanced efficacy of propofol during cardiopulmonary bypass may be due to reduced plasma binding

Angiology - Bilateral internal thoracic artery grafting had no effect on long-term survival in diabetics

Angiology - Deep venous thrombosis has lower incidence in Indian patients

Angiology - Findings in angiology provide new insights

Angiology - In hypercholesterolemic pigs, endothelial permeability to albumin was greater than controls

Angiology - Lacunar infarction patients show no added impairment of cerebral endothelial function

Angiology - Lower ischemic heart disease risk is linked to lower BMI among people in normal BMI range

Angiology - Maximal renal hyperemia is elicited with intrarenal dopamine bolus

Angiology - Myocardial angiogenesis reacts to endostatin in hypercholesterolemic pigs

Angiology - New data illuminates research in angiology

Angiology - Radial artery vasospasm may be due to lack of histamine-induced nitric oxide production

Angiology - Recent findings illuminate research in angiology

Angiology - Recent studies add new data to angiology research

Angiology - Researchers detail new studies and findings in the area of angiology

Anorexia & Heart Abnormalities - Girls with anorexia nervosa show structural and functional cardiac abnormalities

Apoptosis - Cardiac hypertrophy, myocyte apoptosis was decreased by myeloid differentiation factor-88 blockade

Atherosclerosis - Atheroprotective effect of adjuvants is seen in apolipoprotein E knockout mice

Atherosclerosis - Atherosclerosis lesions may evolve from NOR-1 induced vascular endothelial growth factor

Atherosclerosis - Intraluminal aortic manipulation dislodges embolic material

Atherosclerosis - New findings in atherosclerosis described

Atherosclerosis - Progenitor cells comprise the main cell source of atherosclerotic lesions

Atherosclerosis - Researchers' findings advance atherosclerosis research

Biomedical Engineering - Magnetic navigation system for PCI in complex coronary lesions may become useful adjunct

Bladder Cancer - Perioperative mortality from radical cystectomy for bladder cancer analyzed

Breast Cancer - Breast size affected dose delivered by intensity-modulated radiation therapy

Breast Cancer - Potential use of COX inhibitors in breast cancer evaluated

Business Update - CardioVascular BioTherapeutics cofounder discusses future of heart disease therapy

Business Update - Telzuit signs co-marketing, sales agreement with Cardiomedics for wireless monitor system

Cardiac Surgery - Women's high heart-surgery death rate may be due to infection

Cardiology - Arrhythmia pathogenesis may be linked to preproenkephalin gene expression in cardiac hypertrophy

Cardiology - Cardiac angiogenesis may be modified by cyclooxygenase-2

Cardiology - Cavotricuspid isthmus-dependent atrial flutter after left atrial ablation often shows atypical ECG

Cardiology - Early hypertension influences the architecture of myocardial vessel growth

Cardiology - Findings describe new data in cardiology research

Cardiology - In acute MI, levosimendan improves left ventricular diastolic function after angioplasty

Cardiology - Long QT syndrome is exposed by provocation of sudden heart rate oscillation with adenosine

Cardiology - Multiplied rotating waves may be mechanism for acceleration of functional re-entry by rapid pacing

Cardiology - New findings in the area of cardiology described

Cardiology - New findings in the area of cardiology detailed

Cardiology - New onset atrial fibrillation after aortic arch repair is associated with advanced age

Cardiology - New research in the area of cardiology detailed

Cardiology - Post-MI autologous myoblast transplantation increased inducibility of ventricular arrhythmias

Cardiology - Recent findings in cardiology provide new insights

Cardiology - Reduced forearm alpha1 -adrenergic vasoconstriction is associated with heart rate fluctuations

Cardiology - Reports add new data to cardiology research

Cardiology - Reports describe recent advances in cardiology research

Cardiology - Research in cardiology provides new insights

Cardiology - Researchers detail new studies and findings in the area of cardiology

Cardiology - Scintigraphically quantified ischemia correlates with summed ST deviation during coronary occlusion

Cardiology - Studies describe new findings in cardiology research

Cardiomyocytes - In contractile cells, Arg-Gly-Asp-containing peptides increase soluble guanylate cyclase

Cardiovascular Disease - Aldosterone excess has a negative impact on glucose metabolism

Cardiovascular Disease - Cardiovascular mortality correlates with obesity in younger men more than in older men

Cardiovascular Disease - Don't become another statistic: Protect your heart by getting a cholesterol test

Cardiovascular Disease - Recent findings in cardiovascular disease provide new insights

Cardiovascular Disease - Researchers provide details of new studies and findings in the area of cardiovascular disease

Cardiovascular Procedures - Enhanced external counterpulsation reported to reduce angina

Cardiovascular Research - Adenosine- and hypoxia-induced dilation of coronary arteries does not involve KATP channel

Cardiovascular Research - Atrial fibrillation from pulmonary veins may be linked to hyperactive autonomic ganglia

Cardiovascular Research - Extravascular pressure modulates rat coronary artery responses to vasodilator stimuli

Cardiovascular Research - Hemorrhagic shock survival improved with delta opioid pretreatment in rat model

Cardiovascular Research - Higher optimism levels associated with lower risk of cardiovascular death

Cardiovascular Research - Lipid embolization after cardiac surgery is a phenomenon not restricted to brain

Cardiovascular Research - Reduced coronary vascular reactivity is linked to lower functional capacity in women

Cardiovascular Research - TGen survey releases survey data on cardiovascular health of Avondale, Arizona, residents

Cardiovascular Risk Factors - Type 1 diabetes should have early cardiovascular disease risk detection and prevention

Chagas Disease - Night blindness is a new clinical symptom of Chagas disease

Clinical Trials - Acusphere completes enrollment in first of two phase III AI-700 trials

Collaborations - GlaxoSmithKline and Myogen announce pulmonary arterial hypertension partnership

Colorectal Cancer - Venous thromboembolic events linked to breast and colorectal carcinoma diagnoses

Complementary & Alternative Medicine - Patients on statins may benefit from additional LDL-cholesterol lowering with plant sterols

Coronary Artery Bypass - Studies add new findings to coronary artery bypass body of knowledge

Coronary Artery Disease - Diagnosing coronary disease in women may require different clinical approach than in men

Coronary Artery Disease - Oxidation and glycation enhanced LDL effects on PAI-1 production in ECs

Dental Research - Study shows periodontal care lowers cost of medical care when certain diseases are present

Depression - Depression needs to be diagnosed and treated in persons at risk for myocardial infarction

Depression - In depressed patients, brain white-matter hyperintensities correlated with cardiovascular risk

Diabetes & Heart Disease - Diabetes epidemic could erase reductions in deaths, hospitalizations due to heart disease

Diabetes & Stroke - Diabetes and stroke risk management should include multifactorial intervention

Diabetes Complications - ACE inhibitor or angiotensin II receptor antagonist attenuates diabetic neuropathy

Diabetes Complications - Cardiac lipoprotein lipase influence on diabetic heart disease is reviewed

Diabetes Complications - Heart rate variation raises cardiovascular complication risk in diabetics with nephropathy

Diabetes Complications - Heterogeneity of neointimal distribution after bare metal stenting increased complications

Diabetes Complications - Nicorandil before reperfusion on AMI patients with stress hyperglycemia improves outcome

Diabetes Complications - Triacylglycerol turnover kinetics indicate compartmented lipid storage

Diabetes Epidemiology - GST gene variant is linked to elevated inflammation markers and lipid peroxidation in DM

Diabetes Pathogenesis - Fibrinolytic activity is not adversely affected by type 1 diabetes

Diabetes Therapy - Glycemic control does not impact nontraditional cardiovascular disease risk factors equally

Diabetes Therapy - Metformin may improve vascular endothelial functions in diabetes by raising eNOS activation

Diabetes Therapy - Quinapril or losartan improved DAN and LVDD in asymptomatic patients with diabetes mellitus

Diagnostics - Dynamic modeling for ST-segment elevation MI patients enhances risk assessment, management

Diagnostics - Ergonovine test can diagnose vasospastic angina

Diagnostics - Fetal echocardiographic screening for heart defects proves too costly for universal practice

Diagnostics - Myocardial infarct substrate can be localized by dynamic substrate mapping

Diet & Nutrition - Flaxseed is promising for dietary manipulation of hyperlipidemia

Diet & Nutrition - High beta-carotene and beta-cryptoxanthin are associated with low pulse wave velocity

Diet & Nutrition - LifeGuard Health introduces Omega-Cardio nationwide

Diet & Nutrition - Low-carbohydrate appear as effective as low-fat diets in inducing weight loss

Diet & Nutrition - McNeil Nutritionals suggests small steps towards better nutrition and health

Diet & Nutrition - Study of almond board's eating plan suggests heart healthy foods can lower cholesterol

Disease Associations - Researchers' findings advance disease associations research

Drug Development - Ambrisentan ARIES-2 data to be presented at Thoracic Society meeting

Drug Development - Atherogenic inflammation may be target for therapeutic development of mycophenolate mofetil

Drug Development - Cubicin receives positive outcome from U.S. FDA committee, reports Cubist

Drug Development - Takeda selects target for drug development in cardiovascular disease from Lexicon Genetics

Drug Development - Vascular disorders may profit from sphingosine-1-phosphate therapy

Drug Toxicity - Gadolinium-based contrast agents do not reduce nephrotoxicity compared to iodinated contrast media

Echocardiography - New research in the area of echocardiography detailed

Echocardiography - Recent findings in echocardiography described

Electrocardiography - Derived 12-lead electrocardiogram is accurate for assessing ST-segment deviation and cardiac rhythm

Electrocardiography - In myocardial perfusion imaging, high-frequency QRS electrocardiogram predicts perfusion defects

Electrocardiography - Recent findings in electrocardiography provide new insights

Electrocardiography - Sudden death can be predicted by electrocardiographic changes in propofol-related infusion syndrome

Endocrinology - No increased cardiovascular risk if mildly underactive thyroid left untreated

Environmental Health - Admissions for congestive heart failure are linked to increased particulate air pollution

Environmental Health - Researchers report details of new studies and findings in the area of environmental health

Environmental Toxins - Air pollution is linked to daily mortality among persons with diabetes and cardiovascular disease

Epidemiology - CARDIA study indicates oxidative stress generated by adipose tissue lowers carotenoid levels

Estrogen & Heart Disease - Study of early estrogen's effect on heart disease similar to WHI findings

Fetal Cardiology - Fetal echocardiography between 10 and 15 weeks yields data for development and defect detection

Finance - Myogen reports net loss of $63 million or $1.68 per share for 2005

Finance - NMT Medical announces fourth quarter revenues increased 25% to approximately $6.3 million

Finance - Neuromed raises US$25 million, completing fourth-round private equity financing

Finance - Sorin Group reports Q4 2005 net revenue gain of 6.3%, up to $240.8 million over year ago

Fitness & Wellness - VLCAD deficiency is mediated by mitochondrial bioenergetics in BAT in neonates and children

Genetics & Genomics - APM1 gene influences adiponectin plasma levels

Genetics & Genomics - New findings in the area of genetics & genomics detailed

Genetics & Genomics - Researchers' data advance genetics & genomics research

Genetics & Genomics - Researchers' findings advance genetics & genomics research

Gynecology - Hormone replacement therapy does not affect heart disease/overall mortality in older women

Gynecology - Insulin sensitivity may worsen in women using hormone replacement therapy

Head & Neck Cancer - Head and neck cancer treated by amifostine therapy combined with radiotherapy

Head & Neck Cancer - U.S. FDA approves ERBITUX (Cetuximab) for treatment of head and neck cancer

Health Psychology - Vascular reactivity to perceived racism was explored in Black women

Healthcare Costs - Hospital resources are consumed in treating complications associated with PCI

Heart Disease - Researchers fight heart disease with pacing pigs

Heart Disease & Diabetes - hs-CRP was an independent risk factor for coronary heart disease deaths in type 2 diabetics

Heart Failure - Improved compliance of heart failure patients depends on knowledge and change of beliefs

Heart Failure - In patients with heart failure, impaired renal function is a predictor of outcome

Heart Failure - OptiVol fluid accumulation data now accessible via Medtronic CareLink Network

Heart Transplantation - TransMedics announces initiation trial for system to support beating heart transplant

Hematology - Activated coagulation time measurements may vary according to choice of analyzer

Hematology - Coagulation Factor XIII reduces postoperative bleeding after coronary surgery

Hypertension - Findings in hypertension provide new insights

Hypertension - Recent findings illuminate research in hypertension

Hypertension - Recent findings in hypertension described

Hypertension - Research in hypertension provides new insights

Hypertension - Researchers publish new studies and findings in the area of hypertension

Imaging - After transient cerebral ischemia, T1-weighted MR images may represent irreversible tissue injury

Imaging - Data advance knowledge in imaging research

Imaging - Diagnosis of restenosis by transthoracic Doppler echocardiography after PCI is accurate

Imaging - Diastolic heart failure can be diagnosed by comprehensive 2-D and Doppler echocardiography

Imaging - First-pass myocardial perfusion may be assessed visually, semiquantitatively by multidetector CT

Imaging - Imaging of regional myocardial function using Fast-SENC enables single-heartbeat scan duration

Imaging - In acute MI patients, high atherothrombotic burden may be linked to stenting no-reflow phenomenon

Imaging - Left ventricular function is quantified reliably by 16-slice multidetector-row computed tomography

Imaging - Method for characterizing radial undersampling artifacts for cardiac applications is presented

Imaging - New research in the area of imaging detailed

Imaging - One-dimensional acceleration factors enable accurate steady-state free precession CINE MR imaging

Imaging - Plaque variety in proximal coronary system is detected by 64-slice computed tomography

Imaging - Recent findings illuminate research in imaging

Imaging - Recent findings in imaging provide new insights

Imaging - Researchers detail new studies and findings in the area of imaging

Imaging - Researchers provide details of new studies and findings in the area of imaging

Imaging - Researchers publish new studies and findings in the area of imaging

Imaging - Researchers report details of new studies and findings in the area of imaging

Imaging - Researchers' findings advance imaging research

Imaging - Roles of MR imaging and M angiography in congenital diseases of thoracic aorta are considered

Imaging - Siemens Medical introduces dual source computed tomography system

Imaging - Unstable coronary plaque identification by optical coherence tomography is focus of review

Information Technology - SunTech Medical launches interpretive ambulatory blood pressure monitoring software

Ischemia - Ischemic heart disease therapy in women should cater to gender-specific differences

Ischemia - Myocardial ischemia lowers precordial thump efficacy

Ischemia - Recent studies add new data to ischemia research

Kidney Disease - First 'World Kidney Day' calls for early detection and prevention of chronic kidney disease

Kidney Disease - Studies advance knowledge in kidney disease research

Legal Issues - King, Aventis, Cobalt agree to dismiss patent litigation regarding ACE inhibitor Altace

Lipid Research - Downregulation of LDL receptor expression by IL-1 beta alters cardiac lipid metabolism during sepsis

Lipid Research - Titan initiates phase 2 study of DITPA in treatment of elevated cholesterol levels

Marketing - Free online grocery-shopping tool makes heart-healthy shopping easier, faster

Medical Devices - Abiomed shows circulatory support devices at cardiology meeting

Medical Devices - Biosensors' Axxion DES shows positive results in European study

Medical Devices - Large tube section is the key to successful coronary thrombus aspiration

Medical Devices - Merit Medical introduces stiffened dilator mini access kit, S-MAK

Medical Devices - Recent findings in medical devices provide new insights

Medical Education - Multimedia course on aortic valve replacement adapts to individual learning needs

Mergers & Acquisitions - Cardium acquires InnerCool Therapies, a provider of therapeutic hypothermia systems

Mergers & Acquisitions - Covalent enters into combination agreement with Remedium Oy

Mergers & Acquisitions - Royal Philips Electronics to acquire Witt Biomedical Corporation

Metabolic Syndrome - Metabolic syndrome frequency appears to increase throughout menopausal transition

Myocardial Infarction - In postinfarction left ventricular modeling, angiotensin II 1 and 2 receptors are intertwined

Myocardial Infarction - Left ventricular remodeling after myocardial infarction requires histone acetyltransferase activity of p300

Myocardial Infarction - Post-infarction inflammatory response, early LV remodeling are adversely affected by aging

Myocardial Infarction - Researchers reveal secrets of success in the rapid treatment of heart attacks

Myocardial Ischemia - Myocardial ischemia improved after treatment with proangiogenic gene therapy

Neuroscience - Sympathetic nervous dysfunction involving sinus node is present in de novo Parkinson disease

Obesity Complications - Higher BMI is related to right ventricular dysfunction severity in obese and overweight

Obesity Diagnostics - Visceral fat measurement is assessed for ability to predict cardiovascular disease risk

Obesity Epidemic - Poll finds obesity epidemic continues to worsen in the United States

Obesity Pathogenesis - Metabolic syndrome raises CO production to promote hypertension and endothelial dysfunction

Obesity Therapy - New preadipocyte growth media kit for obesity, diabetes, inflammation research introduced

Obstetrics - Angiogenesis factors are implicated in preeclampsia superimposed on chronic glomerulonephritis

Pediatric Cardiology - Norwood procedure survival improved after introducing right ventricle-to-pulmonary artery conduit

Personnel - Charles Mathews joins Lpath board of directors

Personnel - Minneapolis Heart Institute Foundation names James V. Toscano as new president

Pharmaceutical Research - Fenofibrate plus candesartan improves endothelial function and reduces inflammatory markers

Renal Disease - Inflammation in renal disease is focus of review

Restenosis - Insulin resistance triggers arterial hyperplasia despite normoglycemia in rat models

Statins - Data advance knowledge in statins research

Stem Cell Research - Baxter commences phase II adult stem cell trial in patients with coronary artery disease

Stem Cell Research - Embryonic stem-like cells from canine blastocytes isolated and characterized

Stem Cell Research - LifeStem notes significant progress in using stem cells to treat heart disease

Stem Cell Research - Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

Surgical Technology - Aortic aneurysm repair with stented elephant trunk is linked to increased spinal cord injury risk

Surgical Technology - Endovascular stent-graft placement in aortic dissection compares favorably with surgical treatment

Surgical Technology - Fixation of the stent graft in the aortic arch can expand the applicability of endovascular repair

Surgical Technology - For coronary bifurcation lesions, side-access stent proves successful

Surgical Technology - New research in the area of surgical technology detailed

Surgical Technology - Primary aortic co-arctation stenting shows excellent clinical, angiographic outcomes

Surgical Technology - Recent findings in surgical technology provide new insights

Telemedicine - Wireless ECG data recorder integrated into shirt

Thoracic Surgery - Acquired deformities of anterior chest wall are classified with treatment options

Thyroid Disease - Thyroid disease patients' RV function impairments were detected with tissue Doppler

Thyroid Function - Low serum thyrotropin is associated with high plasma fibrinogen

Tissue Engineering - Man-made heart tissue improves cardiac performance

Transitional Cell Cancer - Transitional cell cancer treated by cisplatin, gemcitabine, and weekly docetaxel

Transplant Medicine - Sheet-shaped myoblast graft implantation improved cardiac performance

Type 2 Diabetes - Rosiglitazone and pioglitazone may improve cardiovascular risk in type 2 diabetes mellitus

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