Hypertension
New data illuminates research in hypertension
Published in Heart Disease Weekly, April 11th, 2006
Study 1: Selective angiotensin II receptor antagonism enhances whole-body insulin sensitivity and muscle glucose transport in hypertensive TG(MREN2)27 rats.
"Essential hypertension is frequently associated with insulin resistance of skeletal muscle glucose transport, and angiotensin II(ANGII) can contribute to the pathogenesis of both conditions. The male heterozygous TG(mREN2)27 rat (TGR) harbors the mouse transgene for renin, exhibits local tissue elevations in ANGII and is an excellent model of both hypertension and insulin resistance associated with...
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Source: Heart Disease Weekly (2006-04-11)
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