Cardiovascular Research

Smooth muscle cells from mouse coronary system are isolated and characterized

Published in Heart Disease Weekly, May 2nd, 2006

A recent report describes what may be the first isolation and successful characterization of smooth muscle cells from the mouse coronary system.

According to the report from the United States, "Mice have been used widely in vivo and in vitro cardiovascular research. The availability of knockout mice provides further clues to the physiological significance of specific receptor subtypes."

"Adenosine A₁ receptor (A₁ AR)-knockout (A₁ KO) mice and their wild-type (A₁ WT) controls were employed in this investigation," explained B.Y. Teng and colleagues at East Carolina University in Greenville. "The heart and...

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Source: Heart Disease Weekly (2006-05-02)

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