Vascular Surgery
Vein graft treatment affects collagen and h-caldesmon levels
Published in Heart Disease Weekly, July 2nd, 2006
"The main cause of occlusion and vein graft failure after peripheral and coronary arterial reconstruction is intimal hyperplasia. TGF-beta 1 is a pleiotropic cytokine known to have powerful effects on cell growth, apoptosis, cell differentiation, and extracellular matrix synthesis," wrote R.A. Wolff and colleagues, William S. Middleton Memorial Veterans Administration Medical Center.
They continued, "To investigate the role of TGF-beta 1...
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Source: Heart Disease Weekly (2006-07-02)
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