Cardiology
Researchers from the United States and Netherlands detail new studies and findings in the area of cardiology
Published in Heart Disease Weekly, July 2nd, 2006
Study 1: Cardiac hypertrophy stalls with vascular endothelial growth factor (VEGF)-induced angiogenesis.
"Pressure-overload hypertrophy is associated with decreased capillary density in myocardium resulting in impaired substrate delivery. Treatment of hypertrophied hearts with VEGF induces angiogenesis," scientists in the United States report.
"Since angiogenesis is associated with extracellular matrix degradation, we sought to determine whether VEGF induced angiogenesis in hypertrophy required matrix metalloproteinases (MMP) activation....
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Source: Heart Disease Weekly (2006-07-02)
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