Proteomics
Ischemic and nitroglycerin-induced preconditioning activate MAPKs differentially
Published in Heart Disease Weekly, September 3rd, 2006
According to recent research from Greece, "Previous studies have shown that the cardioprotective effect of ischemic preconditioning (IPC) can be mimicked pharmacologically with clinically relevant agents, including nitric oxide (NO) donors. However, whether pharmacological preconditioning shares the same molecular mechanism with IPC is not fully elucidated."
"The present study aimed to determine the activation of mitogen-activated protein kinases (MAPKs) (ERK1/2, p38 MAPK and p46/p54 JNKs) during ischemia and at reperfusion in...
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Source: Heart Disease Weekly (2006-09-03)
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