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Cardiovascular Disease

Panel recommends values for Lp-PLA2 in assessment of cardiovascular disease risk

Published in Heart Disease Weekly, September 3rd, 2006

diaDexus, Inc. announced the publication of the first recommendations for a proposed cut point for lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme that independently predicts the risk of coronary heart disease and ischemic stroke.

The report was published in the Summer 2006 issue of Preventive Cardiology.

The paper proposes that clinical laboratories set greater than or equal to 235 ng/mL (the median value of the samples analyzed in this study) as the Lp-PLA2 concentration decision value to be used to decide whether patients should be moved to a higher cardiovascular risk category. This cut point is not proposed as a treatment...

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