Cardiovascular Research
Ang II enhances carotid body chemoreflex control of sympathetic outflow in chronic heart failure
Published in Heart Disease Weekly, September 17th, 2006
According to researchers in the United States, "We investigated whether Angiotensin II (Ang II) modulates peripheral chemoreflex function through carotid body (CB) chemoreceptors in chronic heart failure (CHF)."
"We measured renal sympathetic nerve activity (RSNA) in response to graded hypoxia before and after intravenous administration of Ang II (20 ng/kg/min, i.v. 30 min) or AT1 receptor antagonist (L-158,809, 0.33 mg/kg, i.v.) in conscious sham and pacing-induced CHF rabbits," explained University of Nebraska researchers...
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Source: Heart Disease Weekly (2006-09-17)
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