Cardiology
IKr contributes to altered ventricular repolarization that determines long-term cardiac memory
Published in Heart Disease Weekly, September 17th, 2006
According to researchers writing in the journal Cardiovascular Research, "Cardiac memory (CM) is characterized by an altered T-wave morphology, which reflects altered repolarization gradients. We hypothesized that the delayed rectifier currents, IKr and IKs , might contribute to these repolarization changes."
"We studied conscious, chronically instrumented dogs paced from the postero-lateral left ventricular (LV) wall at rates 5-10% faster than sinus rate for 3 weeks," wrote M.N. Obreztchikova and colleagues at...
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Source: Heart Disease Weekly (2006-09-17)
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