Cardiomyocytes
Pro-arrhythmogenic potential of immature cardiomyocytes is triggered by low coupling and cluster size
Published in Heart Disease Weekly, November 12th, 2006
Investigators writing in the journal Cardiovascular Research report, "Cell transplantation strategies to regenerate compromised myocardium take advantage of in vitro generated cardiomyocytes. Common in those immature myocytes is spontaneous impulse formation and a restricted ability to establish proper electrical interaction. Spontaneous impulse formation and impaired cell-to-cell coupling have been shown to be arrhythmogenic."
"To investigate whether these features harbour a pro-arrhythmogenic potential for cell transplantation, a...
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Source: Heart Disease Weekly (2006-11-12)
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