Angiogenesis

Studies from Harvard University yield new information about angiogenesis

Published in Heart Disease Weekly, February 3rd, 2008

According to recent research from the United States, "Growth factor and cell-based angiogenesis are attractive therapeutic options for diabetic patients with end-stage coronary disease. Reduced collateral vessel formation observed in diabetes is associated with increased expression of anti-angiogenic proteins, angiostatin and endostatin."

"The aim of this study was to determine the effects of insulin treatment on the diabetic angiogenic response to chronic myocardial ischemia. Yucatan miniswine were treated with alloxan (pancreatic beta-cell specific toxin, 150 mg/kg) and divided into two groups. In the diabetic group (DM, n = 8), blood glucose levels were kept greater...

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Source: Heart Disease Weekly (2008-02-03)

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