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Amyloidosis



New amyloidosis study findings reported from M. Yamano and co-authors



May 18th, 2008

According to recent research published in the Amyloid - Journal of Protein Folding Disorders, "Senile systemic amyloidosis (SSA) is caused by the deposition of wild-type transthyretin (TTR)-derived amyloid fibrils. This type of amyloidosis is not rare in elderly individuals over the age of 80 and is usually detected on postmortem microscopic examination of myocardium."

"We report a 67-year-old male patient who was clinically diagnosed as having SSA with cardiac involvement. The initial event was cerebral infarction conceivably due to cardiac embolism. Endomyocardial biopsy was performed twice, which led to a definitive diagnosis of amyloidosis at the second biopsy....


Source: Heart Disease Weekly (2008-05-18)