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Heart Disease Weekly

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Heart Disease



New heart disease data have been reported by researchers at Leiden University



December 28th, 2008

"Cholesterol ester transfer protein (CETP) plays an important role in HDL cholesterol metabolism. Leucocytes, including monocyte-derived macrophages in the arterial wall synthesize and secrete CETP, but its role in atherosclerosis is unclear," investigators in Netherlands report.

"The aim of the current study was to investigate the effect of acute coronary syndromes (ACS) on leucocyte CETP expression. Peripheral blood mononuclear cells (PBMCs) were freshly isolated from hospitalized ACS patients displaying Braunwald class IIIB unstable angina pectoris (UAP) on admission (t = 0) and at 180 days post inclusion (t = 180) for analysis of CETP expression. In addition, to...


Source: Heart Disease Weekly (2008-12-28)

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