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Massachusetts General Hospital
Study associates 11 new gene sites with cholesterol, triglyceride levels
December 28th, 2008
An international research team has identified 11 novel locations in the human genome where common variations appear to influence cholesterol or triglyceride levels, bringing the total number of lipid-associated genes to 30. While major mutations in some of these genes have been known to underlie rare lipid metabolism disorders, it is becoming apparent that common changes in the same genes that have modest effects can combine with risk-associated variants in other genes to significantly influence blood lipid levels. The report to appear in the journal Nature Genetics is being released online. "Over the past two years, our work has identified at least a dozen gene regions...
Source: Heart Disease Weekly (2008-12-28)
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