Heart Disease Weekly
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Heart Disease Animal Studies
Data on heart disease animal studies detailed by researchers at Toho University, Department of Cardiovascular Medicine
December 28th, 2008
New research, 'Basic fibroblast growth factor inhibits ventricular remodeling in Dahl salt-sensitive hypertensive rats,' is the subject of a report. According to recent research from Japan, "Basic fibroblast growth factor (bFGF) inhibits the progression of ventricular remodeling in ischemic and hypertensive heart diseases (HHDs). Recent studies have revealed that bFGF induces the transition from myofibroblasts to fibroblasts with decreased expression of alpha-smooth muscle actin (alpha-SMA)." "To clarify the mechanisms underlying the reduced ventricular remodeling in hypertensive heart diseases caused by bFGF, we examined the degree of interstitial fibrosis associated...
Source: Heart Disease Weekly (2008-12-28)
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