Dermatology
Cutaneous manifestations can initiate Waldenstrom macroglobulinemia
Published in Hematology Week, November 10th, 2003
"We report a case of Waldenstrom macroglobulinemia that presented with infiltrated skin nodules and plaques but without systemic symptoms," researchers in England report.
"Cutaneous manifestations such as purpura, edema, urticaria, and ulceration may be seen in Waldenstrom macroglobulinemia and are a consequence of hyperviscosity, cryoglobulinemia and/or tissue deposition of immunoglobulins," wrote I. Chan and colleagues.
The researchers concluded: "Direct cutaneous infiltration by neoplastic lymphoid cells is less common, and very rare as the initial...
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Source: Hematology Week (2003-11-10)
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