Stem Cells

Scientists find genetic "fountain of youth" for adult hematopoietic cells

Published in Hematology Week, November 10th, 2003

Scientists at the University of Michigan (U-M) Comprehensive Cancer Center have identified a gene that controls the amazing ability of adult stem cells to self-renew, or make new copies of themselves, throughout life.

In a series of extensive cell culture and animal studies, U-M scientists discovered that a gene called Bmi-1 was required for self-renewal in two types of adult stem cells - neural stem cells from the central nervous system and neural crest stem cells from the peripheral nervous system. In a previous study, other U-M scientists found that Bmi-1 also was necessary for continued self-renewal in a third variety of blood-forming or hematopoietic stem...

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Source: Hematology Week (2003-11-10)

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