Published in Hematology Week, November 10th, 2003
In a series of extensive cell culture and animal studies, U-M scientists discovered that a gene called Bmi-1 was required for self-renewal in two types of adult stem cells - neural stem cells from the central nervous system and neural crest stem cells from the peripheral nervous system. In a previous study, other U-M scientists found that Bmi-1 also was necessary for continued self-renewal in a third variety of blood-forming or hematopoietic stem...
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