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Hematology Week

Susan Hasty, Publisher

Table of Contents . . . February 16th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Hematology Week | Other Publications

Hemophilia - Neonatal gene transfer leads to tolerance of human factor IX in animal models

B-Cell Lymphoma - Extranodal versus nodal disease at presentation may be clinically important

Breast Cancer Therapy - Cord blood can be excellent source of antitumor T cells

Cancer Research - c-Jun NH2-terminal kinase inhibition arrests growth in multiple myeloma cells

Cancer Survival - Cancer survival survey of Europeans aged 15-24 shows youngest fare worse

Cancer Therapy - Z-100 augments radiotherapy efficacy in melanoma patients

Colon Cancer - Cancer blood test receives certification

Cutaneous Lymphoma - Primary cutaneous B-cell lymphomas may be underdiagnosed in the U.S.

HIV/AIDS Therapy - Enzyme immunoassay enables intracellular nevirapine measurment

Hematologic Toxicities - Hematopoietic growth factors can reduce neutropenia and anemia from chemotherapy

Hemophilia - Treatment for HIV and HCV infections in hemophiliacs reviewed

Transfusion Medicine - Recommendations for managing recalls of blood components released

Kidney Disease - Treatment could change after study of kidney disease

Leukemia - Co-expression of WT1 and MDR1 genes in AML could help determine treatment

Leukemia - FDA approval granted for liquid form of cytarabine injection

Leukemia Diagnostics - WT1 is a poor marker of post-SCT minimal residual disease

Leukemia Pathogenesis - Transient myeloid progenitors can underlie leukemogenesis

Leukemia Therapy - Auto-SCT with costimulated T-cell infusion effective against refractory CML

Leukemia Therapy - Campath-1H does not protect against GVHD in CLL patients

Lung Cancer Therapy - Multimodal treatment effective for elderly SCLC patient

Lymphoma - FDG-PET performed early during chemotherapy may predict lymphoma course

Lymphoma - Quality of life issues are important considerations in cutaneous T-cell lymphoma

Leukemia - Adolescents with ALL may have better outcomes from pediatric oncologists

Lymphoma - Transjugular biopsy useful for primary cardiac lymphoma diagnosis

Lymphoma Therapy - High-dose chemo with CD34+-APBSCT effective against nasal NK/T-cell lymphoma

Malaria Therapy - Novel LC assay accurately measures AQ and AQm in whole blood

Multiple Myeloma - High-, intermediate-dose melphalen regimens compared in multiple myeloma

Multiple Myeloma - Velcade recommended for European marketing approval

Myelodysplastic Syndrome - Novel reduced-intensity SCT safe and effective for MDS treatment

Oncology - Telomerase inhibition is a unique strategy for treating hematological cancers

Pediatric Leukemia - Infection-related complications remain a serious problem in children with AML

Pediatrics - Bone mass tends to improve in thalassemic children at puberty

Platelet Agglutination - Structure of snake-venom toxin convulxin characterized

Stem-Cell Transplantation - Addition of MMF to standard GvHD prophylaxis feasible

Stem-Cell Transplantation - After treatment, SCT is feasible in patients with fungal infections

Stem-Cell Transplantation - Cord blood grafts effective for adult SAA patients

Stem-Cell Transplantation - Features and treatment of vaginal GVHD described

Stem-Cell Transplantation - Highly purified stem-cell grafts have low toxicity in children without malignancy

Stem-Cell Transplantation - Inflammatory myofibroblastic tumors reported in pediatric SCT recipients

Stem-Cell Transplantation - Molecular assay identifies SCT recipients with high AdV infection risk

Stem-Cell Transplantation - Naive T-cell levels in graft correlated with post-SCT naive CD4 cell recovery

Stem-Cell Transplantation - T-cell lymphoproliferative disorders possible after auto-SCT

Thrombocythemia - Reduced Smad4 expression in thrombocythemia may promote megakaryopoiesis

Stem-Cell Transplantation - Unrelated cord blood transplants feasible for adults

Stroke - Clinical features and treatment of pediatric arterial ischemic stroke reviewed

Thrombosis - Enzyme Akt is critical for stabilizing thrombus formation after vessel injury

Transfusion Medicine - Peripheral blood cell separation via surface-modified PU membranes evaluated

Transfusion Medicine - TRALI may be under-diagnosed after stem-cell transplantation

Transplant Medicine - Indiana sees record number of organ transplants in 2003

Acute Myeloid Leukemia - An oral combined regimen for AML had less toxicity and hospitalization

Adverse Drug Effect - Effect of d-fenfluramine on platelet serotonin uptake described

Anemia - First known heart attack associated with beta-thalassemia major reported

Aortic Aneurysm - Aortic aneurysms requires close collaboration with surgical consultants

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