Hematology Week

Breast Cancer - Blood test detects genetic changes in progressive disease

Cancer Surgery - Tumor cells can be removed from blood salvaged during cancer surgery

Cytomegalovirus - CMV viral load can guide clinical management of transplant recipients

Diagnostics - Fixed-trypomastigote EIA may be a suitable candidate for blood bank screening

Leukemia - Hydroxyurea may cause acute leukemia in patients with sickle cell disease

Acute Lymphoblastic Leukemia - Family having hematopoietic cancers poses slight risk of offspring getting ALL

Acute myeloid leukemia - Fusion proteins overcome the hurdle of leukemia cell chemoresistance

Allergy Medicine - Nanocrystalline silver cream potentially therapeutic for skin inflammations

Angiology - Platelet-derived growth factor stimulates pericyte recruitment to tumors

B-Cell Lymphoma - c-FLIP mediates resistance of HRS cells to death receptor-induced apoptosis

Bacteriology - ProSpecT EIA sensitive and specific for Shiga toxin I and 2 detection in stool

Biotechnology - Four pH-dependent formation constants for free PSA elucidated

Blood Shortage - Annual summer blood shortage came early this year for Missouri

Bone Repair - Calcium and thrombin trigger factors that spark endothelial cell proliferation

Breast Cancer - Survivin, Bcl-2, p53 and bax expression increased in breast carcinoma

Cancer Prognosis - Calcitonin gene hypermethylation marks the progress of leukemia

Carcinoma - Bcl-2 expression decreases in endometrial carcinomas

Colorectal Cancer - Alternative genetic pathway to human colorectal cancer found

Complementary & Alternative Medicine - Salicin derivatives from H. cochinchinensis have antiviral activity

Cord Blood - Cancer research foundation offers advice on freezing and saving cord blood

Cord Blood Stem Cells - U.S. Patent Office requested to re-examine cord blood stem cell patent

Coronary Artery Bypass Surgery - Pre-op IgG therapy facilitates off-pump CABG in ITP patient

DNA Damage - Attenuated p53 response in preneoplastic lesions growth advantage under stress

Diabetes Therapy - Ticlopidine beneficial for hypercoagulability in diabetic patients

Drug Development - Bispecific antibody shows promise as lymphoma therapy

Endocrinology - Aldosterone signals modify bone marrow endothelial cell organization

Fungal Infection - Voriconazole may prevent fungal relapse during at-risk periods of leukemia

Genetic Engineering - Administration route shapes the effects of IL-12-expressing dendritic cells

Genomics - Pharmacogenomic profiling of PI3K/PTEN-AKT-mTOR pathway in tumors elucidated

Geriatrics - Plasmid-based hormone therapy could improve disease or age-induced wasting

HIV & Cancer - EBV may play role in pathogenesis of head and neck cancers in HIV infection

HIV and Cancer - Prevalence of lung cancer increased in HIV-infected patients

HIV/AIDS - Co-administration of lopinavir decreases amprenavir concentration

HIV/AIDS - HIV-1 variant in patient with low viral load exhibits RNA dimerization defect

HIV/AIDS - RNAi is gene-specific therapeutic option to control HIV-1 replication

HIV/AIDS Genetics - Multiple viral genes contribute to HIV-associated neuropathy

HIV/AIDS Genetics - Mutations at position 184 of HIV-1 RT affect virus titer and viral DNA synthesis

HIV/AIDS Genetics - Random genetic drift influences HIV-I env evolution during chronic infection

HIV/AIDS Research - Atazanavir and tipranavir quantified in plasma by HPLC plus MS/MS

HIV/AIDS Research - CD4+ and CD8+ T-cell CDR3 clonotype expansion do not correlate with SIV viremia

HIV/AIDS Research - Conserved bulky hydrophobic residues help stabilize HIV gp120-gp41 complex

HIV/AIDS Research - Dendrites cross-present HIV antigens from live and apoptotic infected CD4+ cells

HIV/AIDS Research - Fas and FasL polymorphisms and haplotypes do not correlate with AIDS progression

HIV/AIDS Research - HIV-1 virions induce apoptosis through a CXCR4- or CCR5-dependent pathway

HIV/AIDS Research - Interaction between HIV-1 RT and dNTP substrate contributes to viral mutagenesis

HIV/AIDS Research - SHIVKU-2 infects brain early after infection and persists until the AIDS stage

HIV/AIDS Research - Unusual ''senseless'' 2',5'-oligoribonucleotide has potent anti-HIV activity

HIV/AIDS Treatment - Drug interactions occur between opioids and antiretroviral medications

HIV/AIDS Treatment - Vif-resistant mutant APOBEC3G may provide gene therapy approach to HIV infection

HIV/AIDS Virology - Virologic failure in HIV patients associated with poor adherence to NNRTIs

Heart Surgery - Bivalirudin superior to heparin for thrombosis prevention

Hematology - 1,8-Anilinonaphthalene sulfonate binds to central cavity of human hemoglobin

Hematology - Low-molecular-weight heparins may interfere with tumor growth and metastasis

Hematology - Split-signal FISH detect chromosome aberrations in acute lymphoblastic leukemia

Hemophilia - Immunosuppressive therapy can rapidly resolve acquired postpartum hemophilia

Hepatitis B Virus - Low-level viremia of hepatitis B found in antibody-positive blood donor

Hodgkin Disease - B7-2 protein levels reduced in HD tumor cells

Hodgkin Disease - Cigarette smoking is not associated with a risk of developing Hodgkin disease

Immune Thrombocytopenic Purpura - Rituximab safe and effect for ITP treatment

Immunology - Aberrant MHC class II expression not sufficient to induce thyroid autoimmunity

Immunology - Anti-human olig2 antibody useful marker of normal oligodendrocytes and gliomas

Immunology - CXCL12 mediates CCR7-independent homing of central memory cells

Immunology - Cytosolic phospholipase A₂ alpha targets the phagosome membrane