Stem Cell Transplantation
ATG added to conditioning regimen improves outcome in unrelated donor SCT
Published in Hematology Week, August 2nd, 2004
"We retrospectively analyzed the outcome of voluntary unrelated donor (VUD)-stem cell transplant (SCT) in 56 patients after conditioning without or with ATG. All received partially lymphocyte-depleted grafts," scientists in the Netherlands report.
"Four of 17 patients (24%) who were not given ATG rejected their grafts, as did 1 of 33 (3%) conditioned with ATG (p=.02). The incidences of acute graft-versus-host disease grade III/IV were 29 and 6%, respectively (p=.02), and probabilities of 1-year transplant-related mortality were...
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Source: Hematology Week (2004-08-02)
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