Hematology Week
Susan Hasty, Publisher
Table of Contents . . . August 16th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Hematology Week | Other Publications
Hepatitis C Virus - Transjugular liver biopsy safe in HCV patients with bleeding disorders
Hypertension & Hyperlipidemia - Hypertension and hyperlipidemia - the lower the better
Allergy & Immunology - IL-1 receptor antagonist attenuates airway hyperresponsiveness to ozone
Allergy & Immunology - Interaction between parasitoses and allergy in third world countries elucidated
Allergy & Immunology - Short-term smoke exposure attenuates ovalbumin-induced airway inflammation
Angiogenesis - Bone marrow endothelial cells studied in ongoing angiogenesis
Angiology - Estrogen receptor associated with epithelioid variants of renal angiomyolipoma
Anti-Infectives - Pediatric patients require higher dosages of i.v. voriconazole than adults
Antimicrobials - Response surface approach able to interpret antifungal interactions
Antiretroviral Drug Resistance - Long-term suppression of HIV RNA with HAART occur despite virus evolution
Antiretroviral Therapy - Clusiaceae species extracts inhibit HIV-1 reverse transcriptase
Antiretroviral Therapy - Addition of tenofovir decreases AUC for atazanavir in HIV-treated patients
Antiretroviral Therapy - Atazanavir suppresses HIV with extended use and in nelfinavir-switched patients
Antiretroviral Therapy - Microglia-expressed MRPs may restrict permeation of antiretroviral drugs
Antiretroviral Therapy - Mutation D30N not selected by HIV-1 subtype C in nelfinavir resistance
Antiretroviral Therapy - Novel S-DABO derivatives inhibit HIV-1 and HIV-2
Antiretroviral Therapy - Novel fungal polyketide inhibits HIV-1 integrase activity
Antiretroviral Therapy - Novel thia-DCK analogues inhibit HIV replication in vitro
Antiretroviral Therapy - Previous immunosuppression predicts incomplete immune reconstitution after HAART
Antiretroviral Therapy - Ribinucleotide reductases attenuate efficacy of abacavir
Antiretroviral Therapy - Sustained HIV virological response better with triple nucleoside therapy
Aplastic Anemia - T-cell repertoire returns to normal in HAA recovery
Aspergillosis - ABLC best therapeutic choice to decrease systemic Aspergillus fumigatus burden
Bacterial Resistance - Infection control measures should guide methicillin-resistant S. aureus control
Bacteriology - Clip-and-link activity of repeat in gram-negative pathogen RTX proteins found
Bacteriology - Homologue of aliB found in capsule region of nonencapsulated S. pneumoniae
Biological Markers - DC-SIGN is a marker for dendritic cells and alternatively activated macrophages
Blood Products - Naturlose to be studied to extend blood shelf life
Breast Cancer - Steroid sulfatase inhibitors inhibit MCF-7 breast cancer cell gene activation
Cancer Markers - H3 mRNA level new proliferative marker in astrocytomas
Cancer Metastasis - hsp90 alpha has essential extracellular role in cancer cell invasiveness
Cardiovascular Disease - Recombinant P-selectin glycoprotein ligand-1 prevents in-stent restenosis
Cardiovascular Disease - Ticlopidine, clopidogrel comparably effective during coronary stenting
Cell Culturing - Life science products company obtains CE Mark certification for E.U. sales
Chemokine Receptor - Low pH not required for RANTES or MIP-1beta dissociation from CCR5
Complementary & Alternative Medicine - Cadalene extract exerts antioxidative effect on NNK-induced lung tumorigenesis
Complementary & Alternative Medicine - Ocimum extract and its flavonoids do not protect solid tumors
Coronavirus - Novel peptides inhibit SARS coronavirus
Coronavirus - SARS-associated coronavirus infection inhibited by immoral immune response
DNA Microarrays - DNA microarrays used as a tool in toxicogenomics
DNA Repair - FANCD2 has direct interaction with BRCA2 in DNA damage response pathways
Diagnostics - One-step quantitative RT-PCR assay detects SARS coronavirus
Drug Delivery - New generation of polymer nanoparticles for drug delivery developed
Embroyonic Research - Deletion of P450c17 gene causes early embryonic lethality
Finance - Drug company reports lower sales and earnings for 2004 second quarter
Gene Expression - Hepatocyte nuclear factor-1beta-regulated genes identified
Gene Expression - WT1 gene expression studied as marker for minimal residual disease JMML and MDS
Gene Mutation - One-allele inactivation of AML1 has role in development of overt disease
Gene Therapy - HSV immortalized T cells are gene therapy model for primary immunodeficiencies
HIV/AIDS - Persistent apoptosis in HIV patients associated with poor recovery of CD4 cells
HIV/AIDS Research - AA substitutions in multidrug-resistant HIV RT leads to drug resensitization
HIV/AIDS Research - HIV fitness loss correlates with poor ability of K65R/L74V RT to use nucleotides
HIV/AIDS Research - Insertion of CD80 (B7.1) and CD86 (B7.2) into HIV-1 affects virus life cycle
HIV/AIDS Research - New generation of SNV-based vectors may be used to block HIV-1 replication
HIV/AIDS Research - theta-Defensin composed exclusively of D-amino acids active against HIV-1
HIV/AIDS Screening - Use of two HIV antibody screening tests increase false-positive rate
HIV/AIDS Therapy - Immune recovery slows after 3 years HAART and reaches plateau after 4-5 years
HIV/AIDS Transmission - Acceptance of HAART intervention independent of maternal immune status
HIV/AIDS-Associated Lipodystrophy - Rosiglitazone induces gene expression in adipose tissue in HAL patients
HIV/AIDS-Related Disease - Pneumocystis activates AM NF-KB signaling through mannose receptors
HIV/AIDS-Related Encephalitis - IL-16 expressed in lymphocytes and microglia in HIV-1 encephalitis
HIV/AIDS-Related Lipodystrophy - HIV-related lipodystrophy caused by multiple factors
Heart Failure - Perindopril improves platelet response to sodium nitroprusside in heart failure
Hematology - Circulating endothelial membrane microparticles elevated in hemoglobinuria
Hematology - Monoclonal antibodies as markers of lymphatic vessels studied in horse model
Hemorrhagic Syndrome - Compared drug doses for hemorrhagic syndrome from venomous caterpillar effective
Hepatitis C Virus - Chemokines and CCR5 interaction critical in regulating T cell function
Hepatitis C Virus - CpG oligodeoxynucleotides promising class of drugs for HCV infection
Hepatitis C Virus - Intravenous drug abuse associated with high risk of HIV/HCV coinfection
Herpesvirus - bis(Thiosemicarbazone) compounds active against wild-type and ACV-resistant HSV
Human T Cell Leukemia Virus - HTLV-1 budding impaired at an earlier step than in other retroviruses
Hypercholesterolemia - Cholesterol may be lowered by targeting multiple metabolic pathways
Hypertension - Hypertensive nephrosclerosis linked to obesity/insulin resistance rather than BP
Immunology - Nod2 gene mutation associated with increased chronic inflammation susceptibility
Immunology - TSG-6 modulates the interaction between hyaluronan and cell surface CD44
Leukemia - Novel assay improves assessment of leukemic precursors' lytic susceptibility
Medical Devices - Novel microchip enables direct measurement of lithium in whole blood
Myeloid Graffi Leukemia - Astragalus corniculatus saponins have antitumor effects in hamsters
Neuroscience - Astrocytes contribute to retroviral neuropathogenesis through MCP-1 generation
Pain Markers - Real-time RT-PCR measures spinal glial response marker following nerve injury
Patents - Blood cell container patent for improved cryopreservation issued
Pediatric Cancer - Telomere length, telomerase activity may aid in cancer prognosis, treatment
Peripheral Vascular Disease - R-102444 useful for investigating diseases involving 5-HT2A receptor activation
Pharmaceutical & Drug Development - Mithramycin A sensitizes tumor cells to apoptosis induced by TNF
Pharmaceutical & Drug Development - Novel compounds have antitumor activity
Pharmaceutical & Drug Development - Pyridopyrroloquinoline derivatives are new potential anticancer agents
Phylogenetics - JC virus genotypes used to trace dispersal of Northeast Asians
Reproductive Medicine - Sperm cryopreserved for 21 years before cancer treatment yields live birth
Retrovirus - Antiretroviral therapy suppresses IDO expression in brain during SIV infection
Retrovirus - Hemophagocytic syndrome sign of transformation to adult T-cell leukemia/lymphoma
Retrovirus - SIV-induced metabolic brain abnormalities reversed with virus control
Sepsis - Sepsis-associated gene expression profiles identified
Stem Cell Research - Bipotential embryonic liver stem cells contribute to liver regeneration
Stem Cell Research - Disruption of MKK4 signaling reveals its tumor-suppressor role in ESC
Stem Cell Research - Gamma-aminobutyric acid has role in early neuronal development
Stem Cell Research - Hematopoietic stem cells convert into liver cells within days without fusion
Stem Cell Research - Hepatocytes promote expansion and differentiation of NK cells from SC precursors
Stem Cell Research - Microfluidic PDMS bioreactor developed for large-scale culture of hepatocytes
Stem Cell Research - Osteoblasts are major component of hematopoietic stem cell niche within the BM
Stem Cell Research - Study identifies novel stem cell in blood and vessel formation
Stem Cell Research - Survivin expression in testis upregulated by stem cell factor
Stem Cell Research - bHLH gene over-expression facilitates neural formation of embryonic stem cells
Stem Cell Transplantation - ESHAP regimen cytoreduces resistant myeloma patients
Stem Cell Transplantation - HHV-6 reactivation caused TMA and stroke in SCT and high-dose melphalan patient
Stem Cell Transplantation - HSCT toxic but effective in refractory autoimmune cytopenia patient subset
Thrombosis Therapy - Polymer encapsulation improves plasminogen activator efficacy
Tissue Engineering - Mesenchymal stem cell tissues developed in 3D PET matrices
Tissue Engineering - Polymer-synthesized ceramic composite-based system developed for bone repair
Tissue Factor - Tissue factor's role in angiogenesis, metastasis, embryonic development studied
Tumor Markers - Nestin expressed in some specific cell types from human testicular tumors
Tumorigenesis - Methlonine synthase polymorphism D919G alters susceptibility to CNS lymphoma
Vasculogenesis - Flk-1 target gene identities could elucidate vasculo-, angiogenesis pathways
West Nile Virus - Firms race for dominance of West Nile virus blood testing market
West Nile Virus - Variable size pooling accurately estimates arbovirus vector infection rates
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