Hematology Week

Bone Marrow Transplantation - B-cell depletion in BM transplant correlates with significantly lower EBV load

Cancer Research - Photoactivation of Pba induces mitochondrial-mediated apoptosis in Jurkat cells

Chronic Graft-Versus-Host Disease - Recipient CD4+ T cells that survive irradiation regulate chronic GVHD

Platelets - Insights from different organisms illuminate mechanisms of platelet secretion

Tissue Engineering - Mesenchymal stem cells used for rabbit tendon repair can form ectopic bone

Adenovirus - Genome of human adenovirus serotype 1 sequenced and annotated

Anemia - Anemia in patients with type 1 diabetes reviewed

Angiology - Influence of head position on carotid hemodynamics determined

Antioxidants - Phenolic antioxidants identified in beans inhibit radical-induced DNA damage

Aspergillosis - Liver iron overload after SCT associated with invasive aspergillosis

Awards - Biopharm company is finalist for innovative product award in biotechnology R&D

BK Virus - Full-length BK virus sequence analysis shows high intrastrain genetic diversity

Bioterrorism - New microarray test funded by NIH

Blood Banking - Hamilton Medical selects Care Fusion for barcode lab and blood bank solutions

Blood Disorders - Doctors say Arafat's blood tests reveal low platelet count

Blood Disorders - New quality of life tool available for hemophiliacs

Blood Safety - Blood center offers automated blood collections to address shortage

Blood Safety - Experts to check on possible spread of syphilis through donated blood

Bone Marrow Transplantation - Minority of BMT patients with myeloid leukemia has cognitive/sexual impairment

Burn Injury - BM neutrophil production and release significantly increased after burn injury

Cancer Risk - Raw vegetable consumption decreases cancer risk

Cardiac Arrhythmia - Defibrillator with cardiac rhythm improves response times, is safe, study shows

Cardiogenesis - GATA4 regulates cardiogenesis and is essential for proepicardium formation

Chemoprevention - Antioxidants regulate normal human keratinocyte differentiation

Chikungunya Virus - Chikungunya virus epidemic reemerged in Democratic Republic of the Congo

Colorectal Cancer - Dietary wheat bran and curcurnin protect against colorectal cancer

Cord Blood - No difference in cell cycle status between cord blood and BM or peripheral blood

Dengue Virus - Dengue-2 genotype IV is the predominant and circulating strain in northern India

Disease Prevention - Analysis links breastfeeding to reduced risk of childhood leukemia

Drug Development - Bioreactor company receives National Science Foundation grant

Drug Development - Epigenetic changes in hematopoietic malignancies offer novel treatment tactics

Embolism - Blood-clot imaging technology gets U.S. FDA approval for phase 2 clinical trial

Erythropoiesis - Thrombopoietin and SF have a synergistic effect on primitive stem cells

Escherichia Coli - Pathogen distribution model developed for E. coli O157:H7 in ground beef

Fanconi Anemia - Fanconi anemia gene promotes homologous recombination/error-prone DNA repair

Finance - Biopharmaceutical company reports third quarter results

Finance - Biotech completes new financing

Finance - Pharmaceutical company announces third quarter performance, EPS of $0.60

Foot and Mouth Disease - Presence of viral RNA indicates viral persistence in foot-and-mouth disease

Gene Expression - Gene expression profiling explores hepatocyte/nonparenchymal cell interactions

Graft-Versus-Host Disease - Donor antigen-presenting cells required for maximal GVHD but not for GVL

Graft-Versus-Host Disease - Mycophonolate mofetil added to CsA does not significantly reduce aGVHD

HIV/AIDS Coinfection - High HTLV-1 prevalence in immigrant male-to-female transsexual HIV+ sex workers

HIV/AIDS Drug Resistance - HIV-1 resistance to enfuvirtide characterized by very low genetic barrier

HIV/AIDS Infection - Alcohol abuse associated with increased sexual risk for HIV infection in Africa

HIV/AIDS Research - HIV-1 Tat regulates SOD2 basal promoter by altering Sp1/Sp3 binding activity

HIV/AIDS Research - HIV-1 compartmentalizes in diverse leukocyte populations during HAART

HIV/AIDS Research - Macaques infected with SIV chimera containing HIV-1 RT useful for NNRTI studies

HIV/AIDS Research - Model developed to study function of HIV-infected monocyte-derived macrophages

HIV/AIDS Research - Novel assay identifies entry inhibitors that block HIV-1 gp120 binding to CCR5

HIV/AIDS Research - Proviral clone replicates the same as its parental HIV-1 group O isolate

HIV/AIDS Risk Factor - HSV-2 is key risk factor in promoting HIV transmission

HIV/AIDS Therapy - Antiretroviral drug HpAZT is less cytotoxic than AZT

HIV/AIDS Therapy - HIV-inhibitory cyclic depsipeptide isolated from marine sponge

HIV/AIDS Therapy - Initial indinivir dose should based on patient sex and ritonavir intake

HIV/AIDS Therapy - K65R/Q151M mutations frequently selected during NRTI exposure in HIV-2 infection

HIV/AIDS Therapy - NNRT analog has novel mechanism for HIV RT inhibition

HIV/AIDS Therapy - Novel nonnucleoside HIV-1 RT inhibitors have minimal cytotoxicity

HIV/AIDS Therapy - Synthetic batzelladine analogues inhibit HIV-1 envelope-mediated fusion

HIV/AIDS Vertical Transmission - HIV subtype C preferentially transmitted in utero over subtypes A or D

HIV/AIDS Viral Load - HIV RNA levels differ by sex/risk group/age before ART initiation

HIV/AIDS-Coinfection - HIV-1 transactivated by Mycobacterium tuberculosis-infected macrophages

HIV/AIDS-Related Genomics - (CCR)5-Delta32 polymorphism higher in HIV-negative exposed than HIV+ individuals

HIV/AIDS-Related Kaposi Sarcoma - Serologic response against ORF73 differs between HIV patients with/without KS