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Novel chemiluminescent immunosensor assay detects serum CA19-9 levels

Published in Hematology Week, December 6th, 2004

A novel chemiluminescent immunosensor assay detects serum CA19-9 levels.

"A novel chemiluminescent immunosensor for carbohydrate antigen 19-9 (CA19-9) based on the immobilization of CA19-9 on the cross-linked chitosan membrane was developed. The different membranes were characterized by atomic force microscopy (AFM) and infrared spectrum, respectively.

"Based on a noncompetitive immunoassay format, this proposed chemiluminescent immunosensor enabled a low-cost, flexible and rapid determination for CA19-9 in combination with flow injection analysis (FIA)," wrote investigators in China.

"After an off-line incubation of the analyte...

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